October 2025 in “International Journal of Cell and Biomedical Science” In this study, the application of human umbilical cord mesenchymal stem cell secretome significantly increased hair follicle count in fluconazole-induced alopecia in rats, although changes in epidermal thickness were not significant, suggesting a novel approach for hair restoration.
25 citations
,
May 2013 in “Experimental Dermatology” This study found that topical EGF-liposomal solution may protect hair follicles from chemotherapy-induced damage by inducing a catagen-like stage in a mouse model.
January 2013 in “Seoul National University Open Repository (Seoul National University)” This study found that pretreating hair follicles with epidermal growth factor (EGF) may protect against chemotherapy-induced hair damage by inducing a catagen-like stage, thus supporting primary hair recovery.
12 citations
,
January 2021 in “Journal of Cutaneous and Aesthetic Surgery” This systematic review describes current findings on the use of recombinant epidermal growth factor (rhEGF) for skin aging and wound healing, emphasizing its potential benefits but highlighting the need for more controlled studies to optimize dosing and treatment protocols.
99 citations
,
April 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that human hair follicles serve as a crucial reservoir for Langerhans cells, which repopulate the epidermis depleted by ultraviolet B exposure.