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    Glossary Epidermal Growth Factor Receptor

    protein on cell surfaces aiding growth and division

    The Epidermal Growth Factor Receptor (EGFR) is a protein found on the surface of cells that helps them grow and divide. It is crucial in regulating cell growth, survival, and differentiation. When EGFR is mutated or overexpressed, it can lead to uncontrolled cell proliferation, which is a common feature in various cancers.

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    1. Epidermal Growth Factor
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    Research 10 of 1000+

    1. Epidermal Growth Factor Induces Proliferation of Hair Follicle-Derived Mesenchymal Stem Cells Through Epidermal Growth Factor Receptor-Mediated Activation of ERK and AKT Signaling Pathways Associated with Upregulation of Cyclin D1 and Downregulation of p16 Stem Cells and Development · 2016 · 83 citations
    2. The incidence and management of cutaneous adverse events of the epidermal growth factor receptor inhibitors Postępy Dermatologii i Alergologii · 2017 · 18 citations
    3. BI02 (P97): Epidermal growth factor receptor inhibitor therapy induces a distinct inflammatory hair follicle response that includes a collapse of immune privilege British Journal of Dermatology · 2022
    4. Follicular and epidermal alterations in patients treated with ZD1839 (Iressa), an inhibitor of the epidermal growth factor receptor 2002 · 169 citations
    5. Cutaneous consequences of inhibiting EGF receptor signaling in vivo: Normal hair follicle development, but retarded hair cycle induction and inhibition of adipocyte growth in EgfrWa5 mice Journal of Dermatological Science · 2010 · 32 citations
    6. Role for the Epidermal Growth Factor Receptor in Chemotherapy-Induced Alopecia PLoS ONE · 2013 · 20 citations
    7. Syntaxin 9 is Enriched in Skin Hair Follicle Epithelium and Interacts With the Epidermal Growth Factor Receptor Traffic · 2005 · 13 citations
    8. Suppression of Wnt/β-catenin signaling by EGF receptor is required for hair follicle development Molecular Biology of the Cell · 2018 · 25 citations
    9. KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin Development · 2009 · 82 citations
    10. 546 Epidermal growth factor receptor as a key regulator of the immune privilege Journal of Investigative Dermatology · 2022
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    Community 3 of 9

    1. Does applying Epidermal Growth Factor (EGF) make a difference in hair growth? Reddit · 21 Nov 2022
    2. Scalp slapping to increase blood flow? Reddit · 6 Jun 2024
    3. Comprehensive Microneedling Guide Reddit · 19 Aug 2022
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