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    Did you mean Epidermal Growth Factor Receptor?
    Glossary Epidermal Growth Factor Receptor

    protein on cell surfaces aiding growth and division

    The Epidermal Growth Factor Receptor (EGFR) is a protein found on the surface of cells that helps them grow and divide. It is crucial in regulating cell growth, survival, and differentiation. When EGFR is mutated or overexpressed, it can lead to uncontrolled cell proliferation, which is a common feature in various cancers.

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    Research 30 of 1000+

    1. Epidermal Growth Factor Induces Proliferation of Hair Follicle-Derived Mesenchymal Stem Cells Through Epidermal Growth Factor Receptor-Mediated Activation of ERK and AKT Signaling Pathways Associated with Upregulation of Cyclin D1 and Downregulation of p16 Stem Cells and Development · 2016 · 83 citations
    2. The incidence and management of cutaneous adverse events of the epidermal growth factor receptor inhibitors Postępy Dermatologii i Alergologii · 2017 · 18 citations
    3. BI02 (P97): Epidermal growth factor receptor inhibitor therapy induces a distinct inflammatory hair follicle response that includes a collapse of immune privilege British Journal of Dermatology · 2022
    4. Follicular and epidermal alterations in patients treated with ZD1839 (Iressa), an inhibitor of the epidermal growth factor receptor 2002 · 169 citations
    5. Cutaneous consequences of inhibiting EGF receptor signaling in vivo: Normal hair follicle development, but retarded hair cycle induction and inhibition of adipocyte growth in EgfrWa5 mice Journal of Dermatological Science · 2010 · 32 citations
    6. Role for the Epidermal Growth Factor Receptor in Chemotherapy-Induced Alopecia PLoS ONE · 2013 · 20 citations
    7. Syntaxin 9 is Enriched in Skin Hair Follicle Epithelium and Interacts With the Epidermal Growth Factor Receptor Traffic · 2005 · 13 citations
    8. Suppression of Wnt/β-catenin signaling by EGF receptor is required for hair follicle development Molecular Biology of the Cell · 2018 · 25 citations
    9. KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin Development · 2009 · 82 citations
    10. 546 Epidermal growth factor receptor as a key regulator of the immune privilege Journal of Investigative Dermatology · 2022
    11. Nonscarring inflammatory alopecia associated with the epidermal growth factor receptor inhibitor gefitinib Journal of the American Academy of Dermatology · 2006 · 57 citations
    12. Recent advances in the epidermal growth factor receptor/ligand system biology on skin homeostasis and keratinocyte stem cell regulation Journal of Dermatological Science · 2013 · 97 citations
    13. Vitamin D receptor cross-talk with p63 signaling promotes epidermal cell fate 2023 · 1 citations
    14. β-Catenin–Dependent Wnt Signaling: A Pathway in Acute Cutaneous Wounding [RETRACTED] Plastic and Reconstructive Surgery · 2018 · 13 citations
    15. Effect of Flightless I Expression on Epidermal Stem Cell Niche During Wound Repair Advances in Wound Care · 2019 · 10 citations
    16. Skin toxicity caused by EGFR antagonists—An autoinflammatory condition triggered by deregulated IL‐1 signaling? Journal of Cellular Physiology · 2008 · 19 citations
    17. Deficiency of kinase suppressor of Ras1 prevents oncogenic ras signaling in mice. PubMed · 2003 · 114 citations
    18. VEGF upregulates VEGF receptor-2 on human outer root sheath cells and stimulates proliferation through ERK pathway Molecular Biology Reports · 2012 · 23 citations
    19. A desmosomal cadherin controls multipotent hair follicle stem cell quiescence and orchestrates regeneration through adhesion signaling iScience · 2023 · 1 citations
    20. Transcriptome analysis to identify the downstream genes of androgen receptor in dermal papilla cells BMC Genomic Data · 2022 · 1 citations
    21. MLPH-mediated activation of dermal papilla IGF-1 signaling drives human hair shaft elongation and anagen induction Biomedicine & Pharmacotherapy · 2026
    22. 870 Y27632 promotes proliferation via EGFR signaling in a newly isolated and characterized human primary sebocyte cell line Journal of Investigative Dermatology · 2019
    23. Cutaneous Side Effects in Non-Small Cell Lung Cancer Patients Treated with Iressa (ZD1839), an Inhibitor of Epidermal Growth Factor Acta Dermato Venereologica · 2003 · 116 citations
    24. The Cutaneous Epidermal Growth Factor Network: Can it be Translated Clinically to Stimulate Hair Growth? Dermatology Online Journal · 2009 · 39 citations
    25. Hair Follicle Development of Rex Rabbits Is Regulated Seasonally by Wnt10b/β-Catenin, TGFβ-BMP, IGF1, and EGF Signaling Pathways Animals · 2023 · 1 citations
    26. The Cutaneous Epidermal Growth Factor Network: Can it be Translated Clinically to Stimulate Hair Growth? - eScholarship Dermatology Online Journal · 2009
    27. Differential dependency of unmyelinated and A delta epidermal and upper dermal innervation on neurotrophins, trk receptors, and p75LNGFR. PubMed · 1998 · 122 citations
    28. The Epithelial Stem Cell Niche in Skin Elsevier eBooks · 2017 · 9 citations
    29. Recurrent inverse necrotizing infundibular crystalline folliculitis Journal of Cutaneous Pathology · 2024 · 1 citations
    30. 329 Mechanisms of Cutaneous Adverse Events during Targeted Cancer Therapy 2022