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In this study, researchers identified at least four distinct basal stem cell populations in the human interfollicular epidermis, each crucial for maintaining epidermal communication and homeostasis.

This study found that the absence of laminin α5 in adult mice's epidermal basement membrane led to keratinocyte hyperproliferation and immune cell changes, affecting hair follicle development through altered growth factor expression.

This study found that dendritic epidermal T cells and their exosomes enhance epidermal stem cell proliferation, accelerating wound re-epithelialization in the skin.

This study found that the PP2A-B55α regulatory subunit is crucial for ectodermal development in mice, with knockout embryos displaying severe neural and epidermal defects and failing to survive to birth.

This study utilized a pigmented human epidermal equivalent model to incorporate melanocytes into the epidermis and found enhanced differentiation potential compared to conventional in vitro systems, reflecting in vivo cellular trajectories and highlighting melanocyte-to-keratinocyte communication pathways.