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research Mitotic activity in the epidermis of the rabbit stimulated with local applications of testosterone propionate

25 citations , April 1949 in “The journal of experimental zoology”

This research studied the effect of local testosterone propionate applications on rabbit epidermal mitotic activity but reports no new results.

research A Sensitive Assay for the Enzyme Activity in Hair Follicles and Epidermis that Catalyses the Peptidyl-Arginine-Citrulline Post-translational Modification

3 citations , April 2015 in “Current problems in dermatology”

This study focuses on improving the detection and characterization of an enzyme in guinea pig hair follicles that converts arginine to citrulline, highlighting challenges with assay sensitivity and reproducibility.

research An in vivo comparative study of sonic, desert and Indian hedgehog reveals that hedgehog pathway activity regulates epidermal stem cell homeostasis

99 citations , September 2004 in “Development”

This study suggests that deregulation of sonic and desert hedgehog signaling in mouse skin can lead to altered epidermal stem cell activity and lesions similar to human basal cell carcinoma, indicating these cancers may originate outside the stem cell population.

research Activity of type 1 5α-reductase is greater in the follicular infrainfundibulum compared with the epidermis

12 citations , February 1997 in “British Journal of Dermatology”

This study found that 5α–reductase activity is higher in infrainfundibular keratinocytes compared to interfollicular epidermal keratinocytes, suggesting a potential role in acne-related follicular changes.

research TCF/Lef1 activity controls establishment of diverse stem and progenitor cell compartments in mouse epidermis

91 citations , June 2011 in “The EMBO Journal”

This study demonstrates that hair follicle bulge stem cells can transition into other stem cell compartments, indicating their role in maintaining both hair follicles and sebaceous glands.

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Learn

4 / 801 results

learn Epidermal Growth Factor

learn Low Level Laser Therapy

laser therapy for anti-inflammatory and likely insignificant hair regrowth effects

learn Thymosin Beta 4

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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Community Join

5 / 61 results

community PP405: The Ultimate Hair Loss Drug for Complete Hair Growth

211 upvotes 1 year ago

PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.

community Tazarotene shows strong standalone hair regrowth potential, not just a Minoxidil enhancer. Backed by VEGF, HF regeneration, and angiogenesis pathways. Here’s why.

135 upvotes 1 year ago

Tazarotene shows potential as a standalone treatment for hair regrowth by stimulating new hair follicle formation and promoting angiogenesis, similar to microneedling effects. It can be used topically without minoxidil, but users should start with a low concentration to avoid irritation.

community Keratin microspheres - breakthrough

14 upvotes 2 years ago

A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

community Why you can still look forward to PP405 and JXL-069

22 upvotes 1 month ago

PP405 and JXL-069 are the same compound, but users experienced no results due to flawed application methods. The topical gel formulation of PP405 is designed to target hair follicle stem cells effectively, unlike liquid solutions that fail to penetrate deeply.

community TCA 35% chemical peel, don't try this shit at home.

11 upvotes 7 months ago

The conversation discusses using a TCA 35% chemical peel on the scalp to potentially improve hair growth by addressing fibrosis and enhancing the effectiveness of topical treatments. The user also mentions trying microneedling and other methods like topical metformin and dutasteride for hair regrowth.

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