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    Glossary EDAR gene

    provides instructions for a protein crucial in hair development

    The EDAR gene provides instructions for making a protein that is crucial for the development of hair, teeth, and sweat glands. Mutations in this gene can lead to conditions like hypohidrotic ectodermal dysplasia, which affects these structures, resulting in sparse hair, missing teeth, and reduced ability to sweat.

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    Research 10 of 515

    1. A replication study confirmed the EDAR gene to be a major contributor to population differentiation regarding head hair thickness in Asia Human genetics · 2008 · 89 citations
    2. Combination of Transcriptomics and Proteomics Reveals Differentially Expressed Genes and Proteins in the Skin of EDAR Gene-Targeted and Wildtype Cashmere Goats Animals · 2023 · 1 citations
    3. Mutational spectrum of EDA, EDAR, EDARADD, and WNT10A genes in the largest cohort of Russian patients with hypohidrotic ectodermal dysplasia Orphanet Journal of Rare Diseases · 2026
    4. Investigation of the male pattern baldness major genetic susceptibility loci AR/EDA2R and 20p11 in female pattern hair loss British Journal of Dermatology · 2012 · 38 citations
    5. EDA and EDAR expression at different stages of hair follicle development in cashmere goats and effects on expression of related genes 2020 · 12 citations
    6. EDA2R Is Associated with Androgenetic Alopecia Journal of Investigative Dermatology · 2008 · 82 citations
    7. Fine mapping of the human <i>AR/EDA2R</i> locus in androgenetic alopecia British Journal of Dermatology · 2010 · 28 citations
    8. A Theoretical Model for the Treatment of Androgenetic Alopecia Using the STEAP3 Protein, and the Genetic Challenges of Treating AGA Health Science Reports · 2026
    9. Uncovering the genetic architecture and evolutionary roots of androgenetic alopecia in African men Human Genetics and Genomics Advances · 2025
    10. Uncovering the genetic architecture and evolutionary roots of androgenetic alopecia in African men bioRxiv (Cold Spring Harbor Laboratory) · 2024
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