Search
for

    Did you mean Ectodermal Dysplasia?
    Glossary Ectodermal Dysplasia

    genetic disorders affecting skin, hair, nails, teeth, and sweat glands

    Ectodermal Dysplasia (ED) refers to a group of genetic disorders that affect the development of the ectodermal layer, which is responsible for forming the skin, hair, nails, teeth, and sweat glands. Individuals with ED often experience symptoms such as sparse hair, missing or malformed teeth, and an inability to sweat properly, which can lead to overheating.

    Related Terms

    Research 10 of 1000+

    1. Small molecules facilitate single factor-mediated sweat gland cell reprogramming Military Medical Research · 2022 · 9 citations
    2. Role of the Autoimmune Regulator (<i>AIRE</i>) gene in alopecia areata: Strong association of a potentially functional <i>AIRE</i> polymorphism with alopecia universalis Tissue Antigens · 2002 · 86 citations
    3. Autosomal Recessive Transmission of a Rare KRT74 Variant Causes Hair and Nail Ectodermal Dysplasia: Allelism with Dominant Woolly Hair/Hypotrichosis PLoS ONE · 2014 · 21 citations
    4. Lichen Planopilaris with Pili Torti and Ectodermal Dysplasia: a hair curling case report. Case Reports in Dermatology · 2025
    5. WNT10A mutation causes ectodermal dysplasia by impairing progenitor cell proliferation and KLF4-mediated differentiation Nature Communications · 2017 · 96 citations
    6. Dermatopathology and molecular genetics Journal of The American Academy of Dermatology · 2008 · 12 citations
    7. Polarized microscopy in genetic hair disorders: case series 2025
    8. Biology and Genetics of Hair Annual Review of Genomics and Human Genetics · 2010 · 89 citations
    9. Orai1 expression pattern in tooth and craniofacial ectodermal tissues and potential functions during ameloblast differentiation Developmental Dynamics · 2015 · 15 citations
    10. Current Genetics in Hair Diseases InTech eBooks · 2013 · 1 citations
    All research results →

    Learn

    — no results

    Try a deeper search in learn →

    Community

    — no results

    Try a deeper search in community →