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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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5 / 13 resultslearn Dutasteride
Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity
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diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties
Research
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research Drug Pipeline Q2 2022: A Downturn in Approvals
Drug approvals slowed in 2Q22, but notable drugs like Amvuttra, Camzyos, and Olumiant were approved.
research Role of Drug Repurposing in Sustainable Drug Discovery
Drug repurposing speeds up drug development, saves money, and has led to about a third of new drug approvals.
research Drug News
The FDA approved a new breast cancer treatment, found flu shots may reduce heart risks, questioned the safety of fast-tracked drug approvals, showed statins don't help with certain pneumonia, and approved a new dementia imaging agent.
research Finasteride With Doxazosin To Reduce BPH Progression
research Data-Driven Strategies for Drug Repurposing: Insights, Recommendations, and Case Studies
Drug repurposing can speed up and reduce costs in drug discovery, especially for cancer treatment.
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5 / 1000+ resultscommunity 12M post-op +dutasteride daily / FUE 3000Hairs in Korea
A user shared progress pictures 12 months after a hair transplant and daily use of dutasteride. The conversation discusses the quality of comparison photos and the use of hair fibers.
community Pelage are going to do two phase 3 trials for PP405. How long will it take to complete two phase 3 trials?
Pelage plans to conduct two Phase 3 trials for PP405, a new hair loss treatment, which may take about a year to complete. Users discuss various hair loss treatments, including pyrilutamide, minoxidil, finasteride, and clascoterone, with some expressing impatience over the lengthy trial process compared to faster drug approvals like the COVID vaccine.
community With studies showing that 0.2mg Finasteride is almost as effective as 5mg at reducing DHT, why is every doctor prescribing 1mg?
Finasteride is prescribed at 1mg because it is FDA-approved and proven effective, despite evidence that 0.2mg may similarly reduce DHT. The 1mg dose is more effective for hair growth, and lower doses are less available.
community PP405 Phase 2a press release with early results
PP405 shows promise in hair regrowth, with 31% of participants experiencing over 20% increase in hair density after 8 weeks. Phase 3 trials are expected in 2026, with potential market availability by 2029-2031.
community Oral Dut/Minoxidil for two years - no results.
The user has used oral Dutasteride and Minoxidil for two years without regrowth, despite trying Finasteride and supplements. They consider increasing Minoxidil, adding microneedling, and switching medications, while others suggest RU58841, a hair transplant, or checking for other hair loss causes.