February 2026 in “Colloids and Surfaces A Physicochemical and Engineering Aspects” Using molecular dynamics simulations, this study explored the uptake processes of JAK inhibitors on stratum corneum and hair follicle membranes, revealing a unique interaction mechanism in the hair follicle and offering insights into transdermal drug delivery pathways.
51 citations
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October 2024 in “Pharmaceutics” This review highlights the potential of permeation enhancers to improve the delivery of active ingredients across the skin, optimizing therapeutic outcomes despite challenges posed by individual variability and environmental factors, according to the authors' analysis of current understanding and applications in skincare and transdermal therapies.
47 citations
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June 1996 in “International Journal of Legal Medicine” This article discusses how drug molecules integrate into hair fibers, focusing on biological transport mechanisms and physicochemical factors, but reports no new experimental findings.
202 citations
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June 2005 in “Aaps Pharmscitech” This review discusses the potential of lecithin organogels for improving topical drug delivery and presents no new experimental results; the authors highlight their stability and low skin irritancy as advantages.
4 citations
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February 2021 in “Journal of Pharmaceutical Sciences” This study suggests that the developed PBPK model effectively predicts pharmacokinetic and pharmacodynamic profiles of topical finasteride and minoxidil on the scalp, indicating potential broader applicability for other formulations.