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Canonical and Dominant Negative Peroxisome Proliferator-Activated Receptor Gamma Isoforms Are Differentially Expressed in Human Skin and Skin Appendages

research Canonical and Dominant Negative Peroxisome Proliferator-Activated Receptor Gamma Isoforms Are Differentially Expressed in Human Skin and Skin Appendages

November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

Different types of PPARγ are found in varying amounts in human skin and its parts, which could affect how skin treatments work.

research APCDD1 Is a Novel Wnt Inhibitor Mutated in Hereditary Hypotrichosis Simplex

199 citations, April 2010 in “Nature”

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

Activin Controls Skin Morphogenesis and Wound Repair Predominantly via Stromal Cells and in a Concentration-Dependent Manner via Keratinocytes

research Activin Controls Skin Morphogenesis and Wound Repair Predominantly via Stromal Cells and in a Concentration-Dependent Manner via Keratinocytes

81 citations, September 2005 in “The American journal of pathology”

Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.

research Clinical Snippets: Insights into Dermatological Studies

January 2016 in “Journal of Investigative Dermatology”

Some cells may slow melanoma growth, a protein could affect skin pigmentation, a gene-silencing method might treat hair defects, skin bacteria changes likely result from eczema, and a defensin protein could help treat multiple sclerosis.

research The De Novo DNA Methyltransferase DNMT3A Is Required for Epidermal Homeostasis

May 2018 in “Journal of Investigative Dermatology”

DNMT3A is crucial for healthy skin and hair growth.

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community High Estrogen causing hair loss?

in Treatment 15 upvotes 1 year ago

A 24-year-old male using topical finasteride for hair loss is experiencing thinning despite treatment and has high estrogen levels. He is seeking advice on whether high estrogen could be causing hair loss and how others with high estrogen levels have addressed it.

community Why didn’t Prince William hop on fin/min?

in Finasteride/Dutasteride 718 upvotes 1 year ago

Hair loss discussion explores why Prince William didn't use treatments like finasteride or minoxidil. Reasons include indifference to appearance, potential side effects, and royal responsibilities.

community Being Bald vs Balding - My experience after shaving it off

in Update 217 upvotes 3 weeks ago

A man in his thirties found increased confidence after shaving his head, despite years of hair loss. Others discussed using treatments like finasteride, minoxidil, and hair transplants, with mixed opinions on their effectiveness.

community Finasteride works like viagra for me

in Finasteride/Dutasteride 153 upvotes 5 months ago

Finasteride increased libido for some users, with effects normalizing after a few weeks to months. Other treatments mentioned include Dutasteride and Minoxidil.

community Am I balding? NW -2, on min and fin for 2 weeks now

in Satire 969 upvotes 1 year ago

User discusses hair loss and treatments like Minoxidil and Finasteride. Conversation includes jokes and comments about hairlines and hair growth.

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