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research Drug Repositioning: New Opportunities for Older Drugs

4 citations , January 2019 in “Elsevier eBooks”

This review examines the current landscape of drug repositioning, highlighting that computational methods expand possibilities for reusing existing drugs to treat unmet medical needs. The authors discuss both the potential of these methods and the challenges faced in identifying new therapeutic applications.

research Common Skin Diseases and Metabolic Syndrome: A Proinflammatory Chemokine Perspective

April 2026 in “Metabolites”

This narrative review explores the strong association between various chronic inflammatory skin diseases and metabolic syndrome, emphasizing shared inflammatory pathways and chemokine involvement, though the precise molecular connections remain partially understood.

Characteristics of KRT80 and Its Roles in Neoplastic Diseases

research Characters of KRT80 and its roles in neoplasms diseases

2 citations , May 2023 in “Cancer medicine”

This review reports that KRT80 is overexpressed in various cancers, enhancing cancer cell proliferation, invasiveness, and migration, suggesting it as a potential therapeutic target, though more clinical studies are needed to fully understand its role in cancer prognosis.

Potential Causal Relationship Between Extensive Lipid Profiles and Various Hair Loss Diseases: Evidence From Univariable and Multivariable Mendelian Randomization Analyses

research Potential Causal Relationship Between Extensive Lipid Profiles and Various Hair Loss Diseases: Evidence From Univariable and Multivariable Mendelian Randomization Analyses

April 2025 in “Journal of Cosmetic Dermatology”

This study suggests potential causal associations between certain lipid levels, specifically HDL-C and triglycerides, and alopecia areata, highlighting the importance of lipid management as a therapeutic target.

Identifying Key Components and Therapeutic Targets of the Immune System in Hidradenitis Suppurativa with an Emphasis on Neutrophils

research Identifying key components and therapeutic targets of the immune system in hidradenitis suppurativa with an emphasis on neutrophils

16 citations , September 2020 in “British journal of dermatology/British journal of dermatology, Supplement”

This review explores the role of neutrophil recruitment in the inflammation seen in hidradenitis suppurativa and emphasizes potential therapeutic targets within these pathways, but it reports no new clinical results.

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5 / 655 results

community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens.

2 upvotes 1 year ago

A method for treating androgenic alopecia using minoxidil, antiandrogens, exercise, and cold exposure to promote hair growth. Environmental factors and lifestyle changes, like diet and exercise, can improve treatment effectiveness.

community Research: Minoxidil grows hair by suppressing androgen activity (DHT) in hair follicles.

43 upvotes 6 years ago

Minoxidil may suppress androgen activity in hair follicles, potentially aiding in hair growth and prostate cancer treatment. Users discuss the effectiveness of minoxidil and finasteride for hair maintenance and regrowth, with some preferring topical applications over oral due to safety concerns.

community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

737 upvotes 3 years ago

A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

community Dental Cavitations, Inflammatory Cytokines (RANTES/CCL5) and Hair Loss

2 months ago

Dental cavitations and their potential link to hair loss through systemic inflammation. The user experienced hair regrowth after dental surgery, suggesting a connection between oral health and hair loss, but this theory is not widely accepted or proven.