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GlossaryDifferentially Expressed Proteins

proteins with varying expression levels between different biological conditions

Differentially Expressed Proteins (DEPs) are proteins that show significant differences in their levels of expression between two or more biological conditions, such as healthy versus diseased tissue. Identifying DEPs can help researchers understand the molecular mechanisms underlying various conditions, including alopecia, by highlighting which proteins are upregulated or downregulated in response to specific factors.

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research Combination of Transcriptomics and Proteomics Reveals Differentially Expressed Genes and Proteins in the Skin of EDAR Gene-Targeted and Wildtype Cashmere Goats

1 citations , April 2023 in “Animals”

Deleting the EDAR gene in Cashmere goats affects genes and proteins related to hair growth.

research Proteomics-Based Screening of Differentially Expressed Proteins in Skin of Chinese Merino Fine Sheep (JunKen Type) by Gender

1 citations , October 2022 in “PubMed”

Gender affects wool traits in sheep, with males and females showing differences in skin proteins related to wool growth.

Proteomic Analysis Identifies Differentially Expressed Proteins Participating in Forming Type III Brush Hair in Yangtze River Delta White Goat

research Proteomic Analysis Identifies Differentially Expressed Proteins Participating in Forming Type III Brush Hair in Yangtze River Delta White Goat

8 citations , January 2015 in “Genetics and molecular research”

Researchers found four key proteins that affect the development of a specific hair type in Yangtze River Delta white goats.

research Identification of Skin-Expressed Genes Possibly Associated with Wool Growth Regulation of Aohan Fine Wool Sheep

30 citations , December 2014 in “BMC Genetics”

Certain genes and proteins may influence wool growth in Aohan fine wool sheep.

research Identification of Genes and Proteins Associated with Anagen Wool Growth

10 citations , September 2016 in “Animal genetics”

Researchers identified key genes and proteins linked to wool growth in sheep.

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community New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase

in Research/Science 123 upvotes 1 year ago

Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 1 year ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community Evolution theory: AGA is your body trying to reduce the risk of prostate cancer by exposing your scalp to more UV

in Research/Science 2 days ago

Androgenic alopecia (AGA) might have evolved to reduce prostate cancer risk by increasing UV exposure to the scalp, but this theory is debated. Treatments like minoxidil and finasteride are used for AGA, though the exact causes and evolutionary reasons for hair loss are unclear.

community How to increase Pyri concentration from 0.5% to 1% wihout using more volume ( 2ml x 2 per say for example )

in Chat 6 upvotes 1 year ago

OP wants to increase pyrilutamide concentration from 0.5% to 1% while already using finasteride. Users suggest waiting for a commercial 1% solution and caution against using grey market products.

community Why is nobody studying the difference between donor and balding hair?

in Chat 89 upvotes 1 year ago

The conversation discusses why the difference between donor and balding hair isn't studied more to find a cure for hair loss. Treatments mentioned include Minoxidil, finasteride, and RU58841.

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