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GlossaryDifferentially Expressed Proteins

proteins with varying expression levels between different biological conditions

Differentially Expressed Proteins (DEPs) are proteins that show significant differences in their levels of expression between two or more biological conditions, such as healthy versus diseased tissue. Identifying DEPs can help researchers understand the molecular mechanisms underlying various conditions, including alopecia, by highlighting which proteins are upregulated or downregulated in response to specific factors.

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research Combination of Transcriptomics and Proteomics Reveals Differentially Expressed Genes and Proteins in the Skin of EDAR Gene-Targeted and Wildtype Cashmere Goats

1 citations, April 2023 in “Animals”

Deleting the EDAR gene in Cashmere goats affects genes and proteins related to hair growth.

research Proteomics-Based Screening of Differentially Expressed Proteins in Skin of Chinese Merino Fine Sheep (JunKen Type) by Gender

1 citations, October 2022 in “PubMed”

Gender affects wool traits in sheep, with males and females showing differences in skin proteins related to wool growth.

Proteomic Analysis Identifies Differentially Expressed Proteins Participating in Forming Type III Brush Hair in Yangtze River Delta White Goat

research Proteomic Analysis Identifies Differentially Expressed Proteins Participating in Forming Type III Brush Hair in Yangtze River Delta White Goat

8 citations, January 2015 in “Genetics and molecular research”

Researchers found four key proteins that affect the development of a specific hair type in Yangtze River Delta white goats.

research Identification of Genes and Proteins Associated with Anagen Wool Growth

10 citations, September 2016 in “Animal genetics”

Researchers identified key genes and proteins linked to wool growth in sheep.

research Discovery of Genes and Proteins Possibly Regulating Mean Wool Fibre Diameter Using cDNA Microarray and Proteomic Approaches

6 citations, May 2020 in “Scientific reports”

Researchers identified genes and proteins that may influence wool thickness in sheep.

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community New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase

in Research/Science 120 upvotes 7 months ago

Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 2 months ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community How to increase Pyri concentration from 0.5% to 1% wihout using more volume ( 2ml x 2 per say for example )

in Chat 6 upvotes 3 months ago

OP wants to increase pyrilutamide concentration from 0.5% to 1% while already using finasteride. Users suggest waiting for a commercial 1% solution and caution against using grey market products.

community Why is nobody studying the difference between donor and balding hair?

in Chat 89 upvotes 6 months ago

The conversation discusses why the difference between donor and balding hair isn't studied more to find a cure for hair loss. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Research Backed Dutasteride Simulator (Serum/scalp DHT included for all doses)

in Research 487 upvotes 4 weeks ago

A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalp DHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalp DHT suppression.

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