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Glossary Differentially Expressed Proteins

proteins with varying expression levels between different biological conditions

Differentially Expressed Proteins (DEPs) are proteins that show significant differences in their levels of expression between two or more biological conditions, such as healthy versus diseased tissue. Identifying DEPs can help researchers understand the molecular mechanisms underlying various conditions, including alopecia, by highlighting which proteins are upregulated or downregulated in response to specific factors.

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research Differential gene expression profiles in foetal skin of Rex rabbits with different wool density

4 citations , September 2016 in “World Rabbit Science”

This study observed that gene expression differences in Rex rabbits with varying wool densities suggest the involvement of specific genes and signaling pathways, including Shh and Eph, in hair follicle development.

research m6A Methylation Analysis of Differentially Expressed Genes in Skin Tissues of Coarse and Fine Type Liaoning Cashmere Goats

74 citations , January 2020 in “Frontiers in Genetics”

In this study, the researchers identified key genes with differential m6A methylation involved in cashmere fiber growth, suggesting these modifications may play a significant role in this process.

research Identification of genes and proteins associated with anagen wool growth

10 citations , September 2016 in “Animal genetics”

In this study, researchers identified a number of differentially expressed genes that may influence wool growth in Aohan fine wool sheep, offering insight into the genetic regulation of wool quality and yield.

research A preliminary study of differentially expressed genes in expanded skin and normal skin: implications for adult skin regeneration

16 citations , January 2011 in “Archives of Dermatological Research”

This study identified 77 genes with significant expression changes in expanded human skin, suggesting possible mechanisms for skin regeneration during tissue expansion, including previously unreported genes like HOXA5, HOXB2, and AP1.

research Identification of skin-expressed genes possibly associated with wool growth regulation of Aohan fine wool sheep

30 citations , December 2014 in “BMC Genetics”

This study found thousands of differentially expressed genes and proteins that may be associated with wool growth, suggesting potential gene families involved in hair growth regulation.

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community Evolution theory: AGA is your body trying to reduce the risk of prostate cancer by exposing your scalp to more UV

in Research/Science 9 months ago

Androgenic alopecia (AGA) might have evolved to reduce prostate cancer risk by increasing UV exposure to the scalp, but this theory is debated. Treatments like minoxidil and finasteride are used for AGA, though the exact causes and evolutionary reasons for hair loss are unclear.

community New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase

121 upvotes 2 years ago

Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Dutasteride likely reduces Bone Mineral Density

in Research/Science 5 months ago

Dutasteride may reduce bone mineral density, but there's no increased risk of osteoporosis or fractures compared to finasteride. Users suggest resistance training to counter potential bone effects.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 1 year ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

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