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GlossaryDifferentially Expressed miRNAs

small RNA molecules with varying expression levels in different conditions

Differentially Expressed miRNAs (microRNAs) are small RNA molecules that show different levels of expression in different conditions, such as between healthy and diseased tissues. These variations can help identify specific biological processes or pathways that are altered in conditions like alopecia, providing insights into potential targets for treatment or diagnosis.

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research Effect of Fibroblast Growth Factor 10 and an Interacting Non-Coding RNA on Secondary Hair Follicle Dermal Papilla Cells in Cashmere Goats' Follicle Development Assessed by Whole-Transcriptome Sequencing Technology

2 citations, July 2023 in “Animals”

FGF10 and non-coding RNAs are important for cashmere goat hair follicle development.

research An Integrated Analysis of Cashmere Fineness lncRNAs in Cashmere Goats

26 citations, April 2019 in “Genes”

lncRNA XLOC_008679 and gene KRT35 affect cashmere fineness in goats.

research Comparative Analysis of mRNA and miRNA Expression Between Dermal Papilla Cells and Hair Matrix Cells of Hair Follicles in Yak

December 2022 in “Cells”

Different genes and pathways are active in yak skin and hair cells, affecting hair growth and immune responses.

research Gene Network Analysis Reveals Candidate Genes Related to Hair Follicle Development in Sheep

14 citations, June 2022 in “BMC genomics”

Key genes crucial for sheep hair follicle development were identified, aiding fine wool breeding and human hair loss research.

Time-Course RNA-Seq Analysis Reveals Stage-Specific and Melatonin-Triggered Gene Expression Patterns During the Hair Follicle Growth Cycle in Capra Hircus

research Time-Course RNA-Seq Analysis Reveals Stage-Specific and Melatonin-Triggered Gene Expression Patterns During the Hair Follicle Growth Cycle in Capra Hircus

9 citations, February 2022 in “BMC Genomics”

Melatonin affects gene expression in goat hair follicles, potentially increasing cashmere production.

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community New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase

in Research/Science 119 upvotes 9 months ago

Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 4 months ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community How to increase Pyri concentration from 0.5% to 1% wihout using more volume ( 2ml x 2 per say for example )

in Chat 6 upvotes 5 months ago

OP wants to increase pyrilutamide concentration from 0.5% to 1% while already using finasteride. Users suggest waiting for a commercial 1% solution and caution against using grey market products.

community Why is nobody studying the difference between donor and balding hair?

in Chat 89 upvotes 9 months ago

The conversation discusses why the difference between donor and balding hair isn't studied more to find a cure for hair loss. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Research Backed Dutasteride Simulator (Serum/scalp DHT included for all doses)

in Research 489 upvotes 3 months ago

A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalp DHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalp DHT suppression.

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