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research Unscrewing DHT-Blocking Properties of Allium Cepa Extract: Virtual Screening of active Compounds against 5-Alpha Reductase and Evaluation of Adme/T Properties of Compounds

1 citations , July 2023 in “Zenodo (CERN European Organization for Nuclear Research)”

This study investigates the potential of onion extract as a treatment for androgenetic alopecia by using in silico and ADME/T analyses to examine how active compounds from onions interact with the 5-alpha-reductase enzyme.

research Hormone Blocking Anticancer Drugs

March 2015

The document explains how certain drugs block hormones to treat cancers like breast and prostate cancer.

Ethnopharmacological Review of Medicinal Plants for the Treatment of Alopecia

research Edthnopharmacological Review of Medicinal Plants for the Treatment of Alopecia

March 2023 in “International Journal of Advanced Research in Science, Communication and Technology”

This article discusses various synthetic and herbal treatments for alopecia, noting limited effectiveness and associated side effects of synthetic options, and reports no new clinical results.

research The Antioxidant Activities and Hair-growth Promotion Effects of Tenebrio molitor Larvae Extracts (TMEs)

18 citations , November 2017 in “JoLS Journal of Life Sciences”

This study investigates the effects of Tenebrio molitor as a novel biomaterial for preventing alopecia and promoting hair growth, but reports no conclusive results.

research ESTUDO SOBRE A FINASTERIDA COMBINADA COM MINOXIDIL

January 2023 in “Revista Ibero-Americana de Humanidades, Ciências e Educação”

This source explores treatments for male-pattern baldness, highlighting finasteride, which reduces DHT levels to support hair growth, and minoxidil, used for vasodilation and hair health, though the exact mechanisms remain partly unclear.

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Community Join

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community Blocking dht should bring it back. So why does fin mostly just hold the line?

17 upvotes 3 months ago

Finasteride mainly prevents further hair loss by blocking DHT but doesn't reverse existing damage, while minoxidil can promote regrowth by waking dormant follicles. Ketoconazole helps with inflammation, but none of these treatments can reverse fibrosis or structural changes around hair follicles.

community Hair Loss and Oily Skin: Blocking DHT Helps

in Research/Science 8 upvotes 7 months ago

Lowering DHT can improve skin quality and reduce scalp issues. Finasteride is effective for hair regrowth and improving skin texture, while dutasteride may increase oiliness and shedding for some users.

community Has anyone tried this DHT Blocking Supplement?

4 upvotes 10 years ago

The conversation is about using a DHT-blocking supplement alongside finasteride for hair loss. The user decided against the supplement and increased their finasteride dose from 1 mg to 2.5 mg per day.

community When you think about it blocking dht is not that big of a deal as it’s made out to be

in Research/Science 6 months ago

Reducing sebum can indirectly lower DHT levels, with treatments like accutane, tretinoin, and green tea extract acting as DHT blockers. Accutane can lower DHT levels by reducing 5α-reductase activity, but its impact on hair varies.

community Anagen (@anagenxyz) claiming they've cracked scalp-only DHT blocking - thoughts?

15 upvotes 1 week ago

A company is developing a topical dutasteride that targets hair follicles without significantly affecting systemic DHT levels, with trials underway to measure its effectiveness. Users discuss the potential benefits and skepticism around the formulation compared to existing treatments.

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Learn

9 / 801 results

learn Vascular Endothelial Growth Factor

How does Vascular Endothelial Growth Factor (VEGF) differ from DHT-blocking treatments for androgenic alopecia? VEGF promotes blood vessel growth, while DHT-blocking treatments reduce hormone effects on hair follicles.

learn Clascoterone

a novel topical treatment that inhibits DHT on androgen receptors

learn Cyproterone

a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

learn RU58841

a potent but unapproved and potentially problematic topical anti-androgen

learn Bicalutamide

a nonsteroidal anti-androgen, most commonly used orally for women

Can bicalutamide stop DHT from shrinking your hair follicles? Bicalutamide blocks androgens at the receptor rather than lowering DHT, and some dermatologists prescribe it off-label for women with pattern hair loss. The published evidence is retrospective case series and one small pilot study, with no randomized trial; it is a prescription drug that requires liver monitoring and is contraindicated in pregnancy.

learn GT20029

research compound made to degrade androgen receptors in scalp

learn Exosomes

What does Fluridil do on the scalp, and how does it block the DHT hormone? Fluridil blocks DHT by binding to androgen receptors in hair follicles, preventing hair loss.

learn Metformin

Does metformin help control DHT levels that trigger androgenic alopecia? Metformin has been shown to lower circulating androgens in women with PCOS, but no published study has measured scalp DHT, 5-alpha reductase activity in the follicle, or hair density in anyone taking it — so its effect on pattern hair loss is untested, and it is not a DHT blocker.

learn Vitamin B5

Does Vitamin B5 prevent DHT-related androgenic alopecia? Vitamin B5 does not prevent DHT-related androgenic alopecia.

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Clinics

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