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the gold standard retinoid in dermatology that's also helpful for hair regrowth alongside Minoxidil
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5 / 801 resultslearn Overview
learn GT20029
research compound made to degrade androgen receptors in scalp
learn RU58841
a potent but unapproved and potentially problematic topical anti-androgen
learn Tofacitinib
a JAK inhibitor for alopecia areata and other autoimmune conditions
Research
5 / 1000+ resultsresearch Grand challenges in dermatologic drug discovery: four priorities to transform skin disease treatment
Transforming skin disease treatment requires new strategies, better drug models, and patient-focused research.
research A Review on the Ethnomedicinal Plants Used in Zimbabwe for the Treatment and Management of Skin Conditions: Perspectives on Pharmacological and Toxicological Evaluation
Many plants in Zimbabwe are used for skin conditions, but more research is needed to ensure their safety and effectiveness.
research Ancient-modern concordance in Ayurvedic plants: some examples.
Modern science supports the use of some Ayurvedic plants for health, as ancient practices suggested.
research Montagna Symposium 2017—Precision Dermatology: Next Generation Prevention, Diagnosis, and Treatment
The symposium highlighted the importance of understanding disease mechanisms for targeted dermatology treatments.
research Use of spironolactone in dermatology.
Spironolactone is used in dermatology to treat skin conditions related to hormones, but is not safe for pregnant women or men.
Community Join
5 / 66 resultscommunity We should actually be hopeful for these recent new developments
AI advancements, like AlphaFold, are speeding up drug discovery for hair loss, promising more effective treatments. Current options like minoxidil and finasteride have limitations, but new developments could improve solutions in 5-10 years.
community Wouldn’t it be funny if there already was a drug that existed which reactivated sleeping follicles? It would be our own version of Ozempic
PP405 shows promise for reactivating hair follicles, with potential maintenance using 5AR inhibitors. Current treatments like Minoxidil and finasteride are effective but have limitations, and there is hope for more effective solutions in the future.
community HLT Megathread on HMI-115 (key takeaways in comments)
HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.
community New and Interesting HairLoss Studies/Papers/Reviews
Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.
community Topical Metformin for Hair Transplant donor area skin/hair regeneration?
Topical Metformin shows potential for regenerating hair follicles and minimizing scarring in hair transplant donor areas, similar to Verteporfin but without its side effects. The discussion suggests considering Metformin for post-hair transplant care, though more human trials are needed.