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    Glossary Dermal Sheath Cup Cells

    specialized cells supporting hair follicle growth and regeneration

    Dermal Sheath Cup Cells are specialized cells located at the base of hair follicles. They play a crucial role in hair growth and regeneration by providing structural support and signaling to the surrounding follicular cells, which helps in the cycling and maintenance of hair.

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    Research 10 of 1000+

    1. Autologous cell–based therapy for male and female pattern hair loss using dermal sheath cup cells: A randomized placebo-controlled double-blinded dose-finding clinical study Journal of The American Academy of Dermatology · 2020 · 22 citations
    2. Combatting ageing in dermal papilla cells and promoting hair follicle regeneration using exosomes from human hair follicle dermal sheath cup cells Experimental Dermatology · 2023
    3. High migratory activity of dermal sheath cup cells associated with the clinical efficacy of autologous cell-based therapy for pattern hair loss Journal of Dermatological Science · 2023
    4. Efficacy of autologous dermal sheath cup cell transplantation in male and female pattern hair loss: A Single‐Arm, Multi‐Center, phase III equivalent clinical study The Journal of Dermatology · 2023
    5. 602 Efficacy of autologous cell-based therapy for male and female pattern hair loss using dermal sheath cup cells: A single arm, multi-center, confirmatory clinical study Journal of Investigative Dermatology · 2023
    6. Changes in the Expression of Smooth Muscle Cell–Related Genes in Human Dermal Sheath Cup Cells Associated with the Treatment Outcome of Autologous Cell–Based Therapy for Male and Female Pattern Hair Loss International Journal of Molecular Sciences · 2022 · 2 citations
    7. Morphometric prediction of mesenchymal stromal cell-like immunosuppressive capacity of human hair follicle dermal sheath cup cells: an implication for regenerative medicine in hair loss diseases Stem Cell Research & Therapy · 2025
    8. 281 Phase I/IIa clinical trial for the treatment of androgenetic alopecia using intradermal injections of cultured autologous dermal sheath cup cells Journal of Investigative Dermatology · 2017
    9. Correction to “Efficacy of Autologous Dermal Sheath Cup Cell Transplantation in Male and Female Pattern Hair Loss: A Single‐Arm, Multi‐Center, Phase III Equivalent Clinical Study” The Journal of Dermatology · 2026
    10. Differential Expression of CXCL12 in Human and Mouse Hair: Androgens Induce CXCL12 in Human Dermal Papilla and Dermal Sheath Cup International Journal of Molecular Sciences · 2024
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    Community 2 of 638

    1. New Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness - Paper entitled "Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type" published journal Developmental Cell Reddit · 24 Dec 2014
    2. Shiseido Dermal Sheath Cup (DSC) Hair Multiplication Is Finally in Japan (on July 1) Reddit · 28 Jun 2024
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    Learn 1 of 10

    1. Hair Multiplication extract, clone, and reinsert your own hair cells
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