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research Regulation of the metabolic phenotype of human hepatocytes by glucocorticoids and androgens

December 2016 in “University of Birmingham Institutional Research Archive (University of Birmingham)”

This study found that manipulating 5αR2 activity in human hepatocytes in vitro can regulate lipogenesis, with potential clinical implications for patients taking 5αR inhibitors.

research Quoi de neuf en recherche dermatologique ?

2 citations , December 2011 in “Annales de Dermatologie et de Vénéréologie”

2011 dermatological research found new skin aging markers, hair loss causes, skin defense mechanisms, and potential for new treatments.

research Skin steroidogenesis in health and disease

47 citations , September 2016 in “Reviews in endocrine and metabolic disorders”

This review discusses the steroidogenic properties of human skin and suggests that impaired steroidogenesis may be linked to conditions like acne, rosacea, atopic dermatitis, and androgenic alopecia, but reports no new clinical results.

research A Case of Tricho-rhino-phalangeal Syndrome Caused by a Novel Heterozygous Nonsense Mutation in the TRPS1 Gene

November 2024

A new mutation in the TRPS1 gene caused Trichorhinophalangeal syndrome in a 17-year-old, highlighting the need for genetic testing.

research Vitamin D, Lipid Metabolism and Prostate Cancer

1 citations , January 2009 in “Trepo - Institutional Repository of Tampere University”

This study found that vitamin D regulates cholesterol metabolism and may influence prostate cancer development through mechanisms affecting prostate cell growth and sex hormone metabolism.

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community How much would a high dose dutasteride scalp dht inhibition be?

in Finasteride/Dutasteride 10 upvotes 2 years ago

The conversation discusses the potential for high doses of dutasteride to completely inhibit scalp DHT and speculates whether this could cure baldness when combined with a topical antiandrogen. Specific dosages mentioned are 0.5 mg reducing scalp DHT by 55% and 2.5 mg by about 79%.

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