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Women with PCOS have lower adiponectin hormone levels and are more likely to have insulin resistance.

Foxn1 is important for fat development, metabolism, and wound healing in skin.

Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Postmenopausal women with hyperandrogenism didn't have better metabolic health even after their testosterone levels became normal.

SHBG may be a useful early indicator and treatment target for PCOS.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Melatonin may help treat PCOS symptoms in rats.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Fish oil improves skin health in people with diabetes and high cholesterol.

Losing weight and eating better are key to managing metabolic syndrome and its related conditions.

Obesity is linked to many gastrointestinal diseases and needs more research for treatment development.

Dermal adipose tissue in mice can change and revert to help with skin health.

MFN2 mutations cause mitochondrial problems, leading to more upper body fat and lower leptin levels.

MFN2 mutations cause mitochondrial problems, unusual fat distribution, and low leptin despite high body fat.

The conclusions are: fecal short-chain fatty acids may help prevent cancer, fiber intake can reduce obesity, weight loss is hard for obese people, low BMI cancer patients are more prone to chemotherapy side effects, intermittent fasting benefits gut health, cherry laurel has health benefits in rats, certain gene variations can increase stress in hair loss patients, fecal acids can affect blood sugar levels, cold agglutinin can affect blood test results in autoimmune patients, and people with Crohn's disease have higher levels of a certain chemical in their blood.

SCD1 is crucial for skin health and overall energy balance.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

PTEN helps control the number and health of skin stem cells by working with the protein BMAL1.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Girls with PCOS have higher levels of certain androgens, which are linked to excess hair growth, but these androgens don't help diagnose PCOS.

Anabolic steroids boost muscle growth, SARMs increase muscle mass and bone density without side effects, and myostatin inhibitors block a protein that stops muscle growth, but each has potential risks.

MicroRNAs could be key biomarkers and therapeutic targets for PCOS.

Finasteride may lower cholesterol and slow heart disease progression.

Targeting lipid metabolism can help treat advanced, resistant cancers.