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    Did you mean Cyclin-Dependent Kinase 2?
    Glossary Cyclin-Dependent Kinase 2

    regulates cell cycle progression by partnering with cyclins

    Cyclin-Dependent Kinase 2 (CDK2) is an enzyme that plays a crucial role in regulating the cell cycle, particularly during the transition from the G1 phase to the S phase, where the cell prepares to duplicate its DNA. It works by partnering with specific proteins called cyclins to ensure that cells divide correctly and at the right time, which is essential for normal growth and tissue repair.

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    1. Fatigue, alopecia and stomatitis among patients with breast cancer receiving cyclin-dependent kinase 4 and 6 inhibitors: a systematic review and meta-analysis Expert Review of Anticancer Therapy · 2017 · 28 citations
    2. HIF‐2α/ARNT complex regulates hair development <i>via</i> induction of p21 <sup>Waf1/Cip1</sup> and p27 <sup>Kip1</sup> The FASEB Journal · 2014 · 4 citations
    3. Cyclin-Dependent Kinase 4/6 Inhibitors and Dermatologic Adverse Events: Results from the EADV Task Force “Dermatology for Cancer Patients” International Study Cancers · 2023 · 1 citations
    4. Drug repurposing of cyclin-dependent kinase inhibitors for neutrophilic acute respiratory distress syndrome and psoriasis Journal of Advanced Research · 2024 · 8 citations
    5. Cyclin-dependent kinase inhibitors, p21waf1/cip1 and p27kip1, are expressed site- and hair cycle-dependently in rat hair follicles Journal of Dermatological Science · 2001 · 9 citations
    6. Safety assessment of cyclin-dependent kinase 4/6 inhibitors and comparison of time to adverse events PLoS ONE · 2025 · 2 citations
    7. Understanding The Molecular Mechanisms Of Hair Follicle Stem Cell Quiescence And Genome Plasticity eCommons (Cornell University) · 2013
    8. The Effect of EGR1 on the Proliferation of Dermal Papilla Cells Genes · 2022 · 5 citations
    9. Poster Presentations at the 28th Joint Meeting of the International Society of Dermatopathology, March 5–6, 2025, Orlando, Florida, USA American Journal of Dermatopathology · 2025
    10. Factors regulating quiescent stem cells: insights from the intestine and other self-renewing tissues The Journal of Physiology · 2015 · 8 citations
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