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2 / 2 resultslearn Tofacitinib
a JAK inhibitor for alopecia areata and other autoimmune conditions
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research Method for Quantitative Evaluation of the Effectiveness of Hair Loss Treatments Through Image Analysis: Preliminary Study
The method is effective for evaluating hair loss treatments quickly and affordably.
research The Anxiolytic Effect of Pregnancy in Rats Is Reversed by Finasteride
Pregnancy reduces anxiety in rats, but finasteride reverses this effect.
research The GPI-Anchored Protein Thy-1/CD90 Promotes Wound Healing by Enhancing Skin Perfusion
Thy-1 protein helps improve blood flow and wound healing in the skin.
research Disorders of Hair
The document concludes that hair analysis is not good for assessing nutrition but can detect long-term heavy metal exposure.
research Effect of Temperature and Humidity on Mechanical Properties of Rabbit Hair Fibers
Higher temperatures improve rabbit hair strength up to 50°C, but moisture weakens it.
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5 / 100 resultscommunity Finally Scalp Folliculitis-Free after 2 Decades of Suffering
A 37-year-old male resolved scalp folliculitis by adopting a low-histamine diet and taking Vitamin A, Zinc, and Fish Oil, leading to better skin health and thicker hair. He warns about the potential toxicity of excessive Vitamin A intake.
community Having androgen receptor density and sensitivity at wrong f*ing place
The conversation discusses hair loss treatments, focusing on the use of topical minoxidil, microneedling, finasteride, and dutasteride, while debating the role of testosterone and DHT in hair loss. It also touches on the potential liver health impacts of these treatments and the genetic sensitivity of hair follicles to androgens.
community Diffuse hair loss and scalp biopsies
Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
community Evaluate your progress with an objective tool
The post discusses using ImageJ software to objectively track hair regrowth progress. The user is treating Androgen alopecia with dutasteride and minoxidil.
community FCE 28260: A Forgotten 5α-Reductase Inhibitor
FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.