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research Survey of the Prices of Topical Compounded Medications for Alopecia in the Tri-State Area.

March 2024 in “PubMed”

This survey study reported the pricing, formulation, and delivery options for compounded topical alopecia medications in the tri-state area, finding varied costs and noting the capability of most pharmacies to exceed commercially available minoxidil concentrations and offer delivery services.

research Exploring the Medication Pattern of Externally Used Traditional Chinese Medicine Compound for Hair Loss in the National Patent Database Based on R Language Data Mining

December 2025

This study used R-language data mining to analyze patents of topical Chinese medicine for hair loss, identifying key medication patterns and ingredients in traditional formulations.

research Hair Restoration Techniques

July 2023 in “Facial Plastic Surgery”

This review provides an overview of current hair restoration techniques used in facial plastic surgery, including medications, injections like platelet-rich plasma, light therapy, and follicular unit extraction. Results are not reported.

research Hair: A Review of Prominent Scalp Hair Changes throughout a Females’ Life

January 2014 in “Journal of Pigmentary Disorders”

This review discusses age-related and environmental factors affecting scalp hair changes in women, highlighting diagnostic complexities and ongoing research into targeted treatments, without reporting new clinical results.

research Patient satisfaction, side effects, and other reactions reported by adult men prescribed compounded, topical finasteride via a national telehealth platform: A retrospective analysis of real world data (Preprint)

September 2025

In this large retrospective study, patients using compounded topical finasteride and minoxidil through a telehealth platform for male androgenetic alopecia reported high satisfaction and low incidence of side effects, with no need for higher care or treatment discontinuation due to adverse reactions.

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community God bless this sub and medications!

732 upvotes 11 months ago

The user achieved significant hair regrowth using 0.5mg oral Dutasteride, 2.5mg oral Minoxidil, topical Minoxidil twice daily, Ketoconazole shampoo twice a week, and weekly dermastamping with no side effects. Results were noticeable after 2-3 months, with the best results at 9 months.

community New warning by FDA on topical finasteride

in Research/Science 194 upvotes 1 year ago

The FDA warned that topical finasteride can cause serious side effects like sexual dysfunction and brain fog, similar to oral finasteride. Compounded topical formulations pose additional risks due to lack of regulation.

community Chat is this real? Compound called clascoterone

581 upvotes 9 months ago

Clascoterone shows promising results for hair regrowth in men with androgenetic alopecia, with potential FDA approval by 2026. It acts as a topical androgen receptor blocker, offering a new treatment option with minimal side effects compared to existing treatments like finasteride.

community Dutasteride not working? (Like everyone else)

12 upvotes 4 weeks ago

Dutasteride and oral minoxidil may lose effectiveness when compounded together, as seen in normal DHT levels despite long-term use. Users report varying results with different forms of dutasteride and minoxidil, with some preferring oral over topical due to better outcomes and ease of use.

community Has anyone had success treating androgenic hair loss topically?

4 upvotes 3 months ago

A woman with androgenic hair loss, likely due to PCOS, is seeking topical treatments as oral medications are not an option. Suggested treatments include topical finasteride, spironolactone, and clascoterone, with spironolactone and clascoterone being safer options due to lower systemic absorption risk.

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Learn

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learn Neem Oil

Oil from the neem tree, used in traditional remedies

learn Finasteride

Topical or oral? Choosing between pills and lotions according to your case. In studies, topical finasteride gave much lower blood levels of the drug than tablets but still lowered blood DHT, and whether it causes fewer side effects has not been established. There is no FDA-approved topical finasteride, and the FDA warned about compounded versions in April 2025.

learn TDM-105795

How is TDM-105795 used in hair-related products, and is it being explored as a topical treatment, an oral option, or both? TDM-105795 is not sold in any hair product — it is an unapproved experimental compound. The public trial registry shows it has been studied only as a topical scalp solution, in three completed company trials (the largest a 71-participant, 16-week Phase 2); no oral programme is registered, and no peer-reviewed publication exists.

learn GT20029

Experimental topical drug designed to break down androgen receptors

learn Dutasteride

Dutasteride: What if I just want to grow back some hair without taking pills every day? There is no approved topical dutasteride; it exists only as pharmacy-compounded preparations and small studies, so its effectiveness and long-term safety are not established.

learn Clascoterone

Topical androgen-receptor blocker, approved as an acne cream

learn Fluridil

Topical anti-androgen sold as a cosmetic lotion

learn Pyrilutamide

Experimental topical anti-androgen, also known as KX-826

learn Metformin

Is metformin used topically for hair loss, or only as an oral tablet? Approved metformin products are oral tablets only; there is no approved topical metformin for hair loss. Published human reports of topical use are a handful of uncontrolled, pharmacy-compounded case reports in scarring alopecia, and the most-cited clinical series actually used the oral drug.

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