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      learn Clascoterone

      a novel topical treatment that inhibits DHT on androgen receptors

      learn Neem Oil

      natural substance from Neem tree with medicinal and pesticidal properties

      learn RU58841

      a potent but unapproved and potentially problematic topical anti-androgen

      learn Melatonin

      hormone commonly taken for sleep aid has some topical benefits for hair

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      community New warning by FDA on topical finasteride

      in Research/Science  194 upvotes 1 month ago
      The FDA warned that topical finasteride can cause serious side effects like sexual dysfunction and brain fog, similar to oral finasteride. Compounded topical formulations pose additional risks due to lack of regulation.

      community What happened to topical dutasteride??

      in Finasteride/Dutasteride  28 upvotes 4 months ago
      Topical dutasteride is considered for hair loss, but concerns about systemic absorption and side effects like reduced libido are common. Users have mixed results, with some preferring oral finasteride or dutasteride despite side effects, while others find topical treatments beneficial but challenging.

      community DHT Harms Scalp Microbiome: DHT Itch is REAL

      in Research/Science  404 upvotes 1 month ago
      Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

      community 8 months Oral min and Dutasteride

      in Progress Pictures  62 upvotes 2 months ago
      Oral minoxidil and dutasteride are used for hair loss with mixed results. Some users report new growth, while others suggest scalp inflammation may be an issue.