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Glossary Toxins

harmful substances produced by living organisms causing damage

Toxins are harmful substances produced by living organisms, such as bacteria, plants, or animals, that can cause damage to other organisms. In the context of hair and alopecia, exposure to certain toxins can disrupt normal hair growth cycles, potentially leading to hair loss or thinning. For professionals, understanding the specific biochemical pathways affected by these toxins can aid in developing targeted treatments to mitigate their effects.

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community Another mechanism to hair loss that isn’t talked about. Heavy metals and follicle waste.

16 upvotes 2 months ago

Hair follicles can store waste, potentially leading to hair loss, and treatments like DHT blockers and Minoxidil are suggested. Scalp inflammation and sensitivity to DHT also contribute to hair loss, and addressing these factors with a clinician is recommended.

community If bloodflow, and scalp tightness is cope why does scalp Botox produce results?

5 upvotes 6 months ago

Scalp Botox may help hair loss by relaxing muscles and increasing blood flow, potentially benefiting conditions other than androgenetic alopecia. DHT affects hair follicles differently, causing tension and hair loss in some areas but not others.

community Treatment of Androgenetic Alopecia: Current Guidance and Unmet Needs

3 upvotes 3 years ago

The review discusses traditional hair loss treatments like minoxidil and finasteride, and newer options like Low-Level Laser Therapy, microneedling, and platelet-rich plasma for androgenetic alopecia. It highlights the need for more high-quality trials to assess these treatments' effectiveness and standardized protocols for emerging therapies.

community Noticing hair loss after eating certain foods

3 months ago

The user experiences hair loss and scalp reactions after eating certain non-organic foods, leading them to adopt an all-organic diet which has stabilized their hair condition. Suggestions include using liver-supporting herbs and considering gut health issues like histamine sensitivity.

community If you're worried that you're beginning to develop gyno on fin...

32 upvotes 3 months ago

Finasteride can cause gynecomastia due to increased estrogen from reduced DHT conversion, which some users manage by losing weight and taking supplements like DIM and calcium D-glucarate. Users discuss various experiences with finasteride, dutasteride, and minoxidil, noting side effects and strategies to mitigate them, including switching medications and considering surgery.

community Hair and plants analogy and dht (serious)

2 upvotes 5 months ago

Hair loss may be linked to DHT, which can both suppress and increase inflammation, potentially as a defense mechanism. Treatments like Minoxidil, Finasteride, and RU58841 are discussed, but the exact cause of hair loss remains unclear.

community Hair loss after COVID or vaccination isn’t “made up” but it’s also not what TikTok makes it sound like

2 upvotes 8 months ago

COVID and COVID vaccination can trigger hair loss, primarily telogen effluvium, due to stress and immune system activation. Proper diagnosis and addressing factors like nutrition and stress are crucial for recovery.

community People who continue to lose hair on fin/dut, Are you on Nicotine?

in Research/Science 81 upvotes 1 year ago

Nicotine use, especially from vaping, may worsen hair shedding and reduce the effectiveness of finasteride and dutasteride. Quitting nicotine seems to improve hair health.

community Study: There is 70x Higher Unconjugated DHT in Feces Compared To Blood Levels in Young Adults - Gut Microbiota Manages DHT Recycling and Metabolism

in Research/Science 194 upvotes 1 year ago

Gut microbiota significantly influences androgen metabolism, impacting hair loss treatments like finasteride. Probiotics, dietary changes, and fecal microbiota transplants may help manage DHT levels and improve hair health.

community Losing hair without the white bulb, Tressless GPT's Response. Do you guys agree?

4 upvotes 1 year ago

Hair loss without a white bulb may indicate mechanical damage, anagen effluvium, alopecia areata, or traction alopecia. Seeking a specialist is recommended, but access can be difficult in smaller areas.

community What do people think about using a castor oil pack on thinning hair? It is ant-inflammatory has a lot of vitamins and fatty acids..

4 upvotes 8 years ago

Castor oil is being considered for hair thinning, with some users noting it may prevent hair breakage but not affect DHT-related hair loss. Some users report mixed results, with one mentioning increased body hair growth from oral consumption.

community PP405 is NOT gray market jxl069

in Technology 26 upvotes 8 months ago

PP405 is a safer alternative to JXL069 for hair loss treatment because it penetrates the skin effectively and degrades in the blood, avoiding systemic toxicity. JXL069, when forced into the body, can cause dangerous side effects like lactic acidosis due to its inability to degrade safely.

community Minox 3mg, Finasteride 1.2mg (6 month perfect adherence)

370 upvotes 5 months ago

Significant hair improvement was achieved using 3mg Minoxidil and 1.2mg Finasteride over six months, with no side effects, leading to reconsideration of a hair transplant. A detailed skincare routine, including tretinoin and SPF, also improved skin appearance.

community Here are the steps I'm taking in my hair regrowth journey!

4 upvotes 6 months ago

A user shares their hair regrowth journey using finasteride and minoxidil, highlighting lifestyle changes to enhance results. Another user reports negative side effects from finasteride and plans to try ketoconazole shampoo and natural oils.

community Hair loss research is a money grab

227 upvotes 10 months ago

Hair loss is linked to DHT, with treatments like finasteride and minoxidil being common but not definitive. Economic interests influence research, and there is potential for new treatments like PP405 and RU58841.

community Why don’t more people use hair fibers?

in Product 527 upvotes 10 months ago

Hair fibers can effectively cover thinning hair when used with minoxidil and hairspray but require daily application and can be inconvenient in certain conditions. Some users prefer treatments like finasteride, dutasteride, microneedling, or wigs due to the maintenance and limitations of hair fibers.

community Is this real chat? Finasteride -> fountain of youth and longevity drug?

559 upvotes 1 year ago

Finasteride is discussed as a hair loss treatment with benefits like reduced prostate enlargement and skin aging, but it is not seen as a "fountain of youth." Users report mixed experiences, including side effects like decreased libido and dry eyes.

community Oral Minoxidil- Be Careful!!!!!

in Minoxidil 417 upvotes 1 year ago

Oral minoxidil can cause severe side effects, including heart issues, even at low doses. Users suggest starting with a lower dose or using topical treatments to minimize risks.

community Why do we get bald from evolutionary perspective

in Chat 213 upvotes 1 year ago

Baldness is not an evolutionary disadvantage because it occurs after reproductive age. Treatments like Minoxidil and Finasteride are used for androgenetic alopecia but don't address the root cause.

community British tabloid dutasteride fear mongering

in Chat 103 upvotes 1 year ago

The conversation discusses the impact of hair loss treatments like dutasteride and finasteride, with some users expressing skepticism about media claims linking these drugs to severe side effects like suicidal ideation. Many participants criticize the media, particularly British tabloids, for fearmongering and emphasize the psychological impact of hair loss itself.

community Creatine paired with Finasteride

22 upvotes 1 year ago

Finasteride and creatine are discussed for hair loss, with mixed opinions on creatine's impact. Some users report no hair loss with creatine, while others experience shedding, but finasteride is generally seen as effective.

community Please can someone explain all the Dutasteride horror stories on here

in Finasteride/Dutasteride 114 upvotes 1 year ago

Switching from finasteride to dutasteride for hair loss yields mixed results, with some users experiencing improvements and others facing worsening conditions or side effects like shedding. Patience is advised as dutasteride may take longer to show results, and combining treatments is suggested by some users.

community Balding at 19 should not be a thing

in Treatment 94 upvotes 1 year ago

A 19-year-old is experiencing hair loss and considering treatments like finasteride, oral minoxidil, and possibly dutasteride. Users suggest continuing with finasteride and minoxidil, with some recommending dutasteride for stronger results.

community Anyone else realize how many younger guys are balding?

in Chat 262 upvotes 1 year ago

Many younger men are experiencing hair loss due to genetics, diet, stress, and lifestyle changes. Treatments like finasteride and minoxidil are mentioned, with some users noting improvements.

community Doctor won’t put me on fin or dut until my wife gives birth. Is this normal?

10 upvotes 2 years ago

A doctor advised against using finasteride or dutasteride during pregnancy. The user continues with oral and topical minoxidil, microneedling, tretinoin, Nizoral, and pyrilutamide.

community Quit vaping/smoking = 80% less loss

in Research/Science 235 upvotes 2 years ago

Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

community Oral Minoxidil and Grapefruit Juice

in Research/Science 96 upvotes 3 years ago

The conversation is about the potential dangers of taking oral minoxidil and grapefruit juice together. Some users express concern about dangerous drug interactions, while others argue that grapefruit juice may inhibit the metabolism of finasteride. The conclusion is that grapefruit juice may make finasteride less effective, but it won't affect minoxidil.

community Suffering from intense sides from dutasteride

17 upvotes 8 years ago

A person experienced severe sexual side effects, including loss of libido and erectile dysfunction, after using finasteride and dutasteride for hair loss. They stopped the medications and sought advice, but recovery was slow and uncertain.

community I’m looking to get a hair transplant but I have had contradicting feedback from different consultations

37 upvotes 3 weeks ago

A 22-year-old stabilized hair loss with oral finasteride and minoxidil but sees minimal regrowth. They received conflicting transplant advice, with graft recommendations from 1,600 to 4,000, and concerns about diffuse thinning and donor area.

community Why Fin/Dut Isn't Working for You GPR133: a new hairloss mechanism + Steroid Hair Loss Deep Dive

6 upvotes 1 month ago

Hair loss may be linked to the GPR133 receptor, independent of the androgen receptor pathway. Treatments like finasteride, dutasteride, minoxidil, RU58841, and KX-826 show varying results, with hair loss persisting due to high testosterone and GPR133's role.