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GlossaryT cell activation (T lymphocyte activation)

process where T cells respond to specific antigens

T cell activation is the process by which T cells, a type of white blood cell, are triggered to respond to pathogens or infected cells. This occurs when T cells recognize specific antigens presented by other cells, leading to their proliferation and differentiation into effector cells that can directly attack infected cells or help coordinate the immune response.

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community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community The Worst Hair Loss Condition You (MAY) have: LPP

in Research/Science 43 upvotes 2 months ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community Lost density 60% all over scalp in 120 days (4months)

in Update 10 upvotes 5 months ago

A user lost 60% hair density in 4 months, started finasteride and microneedling, and has greasy, flaky, yellowish scalp. They are awaiting biopsy results, and another user suggested trying ketoconazole shampoo.

community Don't know how but this is an accurate depiction

in Satire 265 upvotes 2 months ago

The conversation humorously discusses hair loss treatments, including topical finasteride, oral dutasteride, topical minoxidil, RU58841, peppermint oil, and microneedling. It also mentions lifestyle changes like converting to Islam and avoiding smoking, drinking, and partying.

community Shouldn’t it be impossible for dutasteride to make hair loss worse?

in Finasteride/Dutasteride 39 upvotes 3 months ago

Dutasteride is unlikely to worsen hair loss; shedding is often temporary. Other factors like inconsistent use, placebo effect, or additional treatments may influence perceived results.

community Don't discount diet for the sake of scalp health. Meds had no effect for 2+ years. 3.5 months since new diet / Shampoo routine.

in Progress Pictures 302 upvotes 4 months ago

Diet and specific shampoo improved scalp health and hair regrowth for someone with seborrheic dermatitis, while medications like Minoxidil and finasteride had no effect. A low-sugar, keto diet was key to their success.

community Can't stop shedding(over 200 hairs a day) 17.5M

in Finasteride/Dutasteride 10 upvotes 4 months ago

A user has been using Topical Finasteride and Minoxidil for 10 months but continues to shed over 200 hairs daily, with minimal improvement. They are seeking advice on whether increasing the finasteride dose might help.

community Isn’t Minixidilmax’s PG solvent just superior to the Anageninc K&B solvent

in Product 1 upvotes 4 months ago

PG solvent is considered superior to K&B solvent for RU58841 and Pyralutamide due to cost and effectiveness. The user questions why they should use K&B when PG offers more benefits.

community Don’t let them scare you from finasteride. 8 months

in Progress Pictures 272 upvotes 4 months ago

A user shared their 8-month progress using 1mg oral finasteride with no side effects and plans to start minoxidil. Another user commented that the results look great and suggested reconsidering starting minoxidil.

community Don't leave a boy hanging, try to help.

in Chat 113 upvotes 4 months ago

A user shared their success with oral finasteride and topical minoxidil for hair loss, recommending these treatments to others. They emphasized the importance of informing others about effective treatments rather than relying on supplements.

community DON'T Lose hope . Long term FIN + MIN + DERMAROLLING

in Update 413 upvotes 5 months ago

A user shared their 4-year hair loss journey, highlighting that switching from topical to oral minoxidil and finasteride, along with dermarolling, significantly improved their hair growth. Another user mentioned using dutasteride, and the original poster emphasized the importance of dermarolling.

community Don't start treatment TOO LATE

in Finasteride/Dutasteride 156 upvotes 5 months ago

Start finasteride and minoxidil early to prevent significant hair loss and maintain styling options. Finasteride can reduce acne and improve skin appearance.

community Don't stop taking minoxidil no matter what

in Minoxidil 9 upvotes 5 months ago

The conversation is about hair loss treatments, specifically minoxidil, finasteride, and dutasteride. The main advice is to start with finasteride and never stop minoxidil once started, as stopping can lead to significant hair loss.

community Can’t believe what i saw after my recent haircut 5% minoxidil + dermaroll + fin

in Progress Pictures 1043 upvotes 6 months ago

User experienced increased confidence and thicker hair after using minoxidil and finasteride for three months. No side effects were reported.

community Don't give up! 9 months on Minoxidil

in Progress Pictures 392 upvotes 6 months ago

A trans man shared progress pictures showing significant hair regrowth after 9 months on oral Minoxidil and 1.5 years on finasteride. He encourages others to stick with their treatments despite initial setbacks.

community Can’t tolerate oral fin at any dosage, help me brainstorm a treatment plan.

in Treatment 9 upvotes 6 months ago

The user cannot tolerate oral finasteride and is considering topical finasteride, minoxidil, microneedling, and RU58841 as alternative treatments for hair loss. They seek advice on whether these options are worth trying.

community Haven’t taken any good pictures, but is it working?

in Is this regrowth? 11 upvotes 8 months ago

The conversation discusses hair regrowth, with the user using finasteride (1 mg), topical minoxidil, and microneedling. A reply suggests the user's hair appears fuller and healthier.

community Didn’t fully realize what a dramatic difference 3 years of (mostly) consistent finasteride made until I stumbled across this photo.

in Progress Pictures 525 upvotes 8 months ago

The conversation is about the significant hair regrowth a person experienced after three years of using finasteride. People are expressing surprise and congratulations on the noticeable improvement.

community Couldn’t be more happy! 5 Months Fin and Min, 19M

in Progress Pictures 346 upvotes 10 months ago

A 19-year-old man is happy with his hair regrowth after 5 months of using finasteride and minoxidil, and he also found a supportive girlfriend while dealing with hair loss and acne. He emphasizes patience and taking progress photos for those struggling with similar issues.

community Didn’t realize how much volume was added until recently (1.5 yr on fin, 6 months on min)

in Progress Pictures 69 upvotes 1 year ago

The conversation discusses hair loss treatment progress, with the user being on finasteride for 1.5 years and minoxidil for 6 months. They mention experiencing occasional erectile dysfunction as a side effect.

community Can’t tell if my hair is growing or not.

in Is this regrowth? 39 upvotes 1 year ago

The user has been treating their hair loss with oral Minoxidil, Dutasteride twice a week, daily head massages, a mix of essential oils, and one round of Scalp Micropigmentation (SMP). They stopped micro-needling due to hair loss, and are seeking advice on their progress, with responses suggesting continued treatment, potential hair transplant, and resuming micro-needling.

community Wasn’t hmi-115 phase 1 supposed to end in july? We’ve heard nothing so far

in Research/Science 10 upvotes 1 year ago

The conversation is about the delay in receiving updates on the HMI-115 phase 1 trial for hair loss. No specific treatments are mentioned in the conversation.

community Can't find 2% keto in my region

in Ketoconazole 21 upvotes 1 year ago

User can't find 2% keto shampoo in their area and asks about ketoconazole BP20. Replies confirm that 20mg/ml means 2% ketoconazole and BP stands for British Pharmacopoeia, ensuring purity and quality standards.

community Can’t do finasteride. Does this automatically cross out Pyrilutamide?

in Research/Science 3 upvotes 1 year ago

Hair loss discussion includes finasteride intolerance and questioning if Pyrilutamide is an alternative. Pyrilutamide not commercially available, but may be tolerable if approved since it's not a 5aR inhibitor.

community Can’t believe i used to look like this. Oral fin, topical min 5 months progress.

in Progress Pictures 270 upvotes 1 year ago

User shared 5-month progress using oral finasteride and topical minoxidil for hair loss, improving from Norwood 3 to Norwood 1. User also mentioned weight loss after a breakup and starting gym alongside hair loss treatment.

community Don’t trust everything y’all are hearing about Pyrilutamide

in Research/Science 10 upvotes 1 year ago

The conversation warns about taking information on pyrilutamide with skepticism, suggesting that many may not have the genuine product. It advises to wait for FDA approval for reliable information.

community Can’t compete with this kid (6 months: 1mg finasteride, 2mL minoxidil daily)

in Progress Pictures 1 year ago

TurboMoe has been using 1mg finasteride and 2mL minoxidil daily for 6 months to reverse his frontal hair loss, with good results. He previously used finasteride in his 20's but stopped before having children due to low sperm count; he stayed off it until his last child was born.

community Don’t call it a comeback! Progress pics. 4/14/22- 1/13/23. Been on Fin 1mg daily, min once a day and Keto 2% twice a week.

in Progress Pictures 67 upvotes 1 year ago

The user's progress with hair loss treatments, including Fin 1mg daily, Minoxidil once a day and Keto 2% twice a week. Another user commented in response.

community Don't give up, guys. It might take a little bit of time, but damn it's worth it. Almost 2 years on fin (8 months dut) + topical minox every day, started oral minox few days ago.

in Progress Pictures 84 upvotes 2 years ago

User improved hairline with 2 years on finasteride (8 months dutasteride) and daily topical minoxidil, recently started oral minoxidil. No side effects experienced, and user's doctor approved dutasteride for a boost.

community Don’t give up on your dreams! fin (most days.. don’t always remember) and minoxidil foam twice a day (when I remember.. at least once a day though) ….and derma roll when I remember (kinda once every 2 or 3 weeks… ye ye.. I know.. I should do it every week but I’m forgetful 😂 )

in Progress Pictures 2 years ago

.. This user has seen positive results from using finasteride and minoxidil foam, as well as derma rolling, to treat their hair loss over the course of a year. They have shared their progress photos with other users for inspiration.