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GlossaryAndrogenetic Alopecia

genetic hair loss influenced by androgens, often hereditary

Androgenetic Alopecia, commonly known as Male Pattern Baldness or Female Pattern Baldness, is a genetic condition characterized by progressive hair thinning and loss. It is influenced by androgens (male hormones) and typically follows a recognizable pattern, such as a receding hairline in men and diffuse thinning on the crown in women. This condition is the most common cause of hair loss, affecting both genders, and is often hereditary.

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Tracking 13 products like 100 RU58841 Powder, 14 Topical Finasteride & Minoxidil Spray, 16 Oral Finasteride, 41 Minoxidil and 154 Duprost from by companies like MinoxidilMax, Hims, Roman and Inhouse Pharmacy. View all 13 products »

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community Treatment of male androgenetic alopecia with topical products containing Serenoa repens (Saw Palmetto) extract.

3 upvotes 9 years ago

The conversation discusses treating male pattern baldness with topical products containing Saw Palmetto extract. Specific treatments mentioned include Minoxidil, Finasteride, and RU58841.

community Comparison of the efficacy of topical minoxidil 5% and adenosine 0.75% solutions on male androgenetic alopecia and measuring patient satisfaction rate

in Minoxidil 15 upvotes 6 years ago

Comparing the effectiveness of minoxidil 5% and adenosine 0.75% for treating male androgenetic alopecia, and measuring patient satisfaction rate; results showed that adenosine is comparable to minoxidil but provides quicker results, however availability of products with adenosine is much less than those with minoxidil.

community Kintor Pharma Announces Completion of Subject Enrollment in Phase III Clinical Trial of KX-826 for Treatment of Male Androgenetic Alopecia

in Research/Science 82 upvotes 1 year ago

Kintor Pharma completed enrolling subjects for a Phase III trial of KX-826 for male hair loss treatment. The trial includes a 24-week treatment period and a 4-week safety follow-up, with results expected in about 6-7 months.

community COMPLETE OVERVIEW of the Treatment of androgenetic alopecia in men

26 upvotes 10 years ago

Male androgenetic alopecia is commonly treated with topical minoxidil and oral finasteride, both requiring continuous use. Other options include hair restoration surgery, dutasteride, light therapy, and camouflaging agents.

community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

in Research/Science 134 upvotes 8 months ago

The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

community Why haven’t we seen anything about this

in Research/Science 18 upvotes 4 years ago

A double blind, placebo-controlled study that looked into the potential effectiveness of topical fluridil for treating male androgenetic alopecia, showing increased anagen to telogen ratios with no reported side effects on libido or sexual performance.

community SCUBE3 and GT20029 could be the closet thing to a cure: Hair Follicle Regeneration and Protection Against DHT

in Research/Science 15 upvotes 1 year ago

SCUBE3 and GT20029 are potential treatments for hair loss, with SCUBE3 stimulating hair growth and GT20029 protecting against DHT. A combined approach using SCUBE3, finasteride or dutasteride, and later GT20029 could provide a comprehensive treatment for androgenetic alopecia.

community Evidenced Based Meta-Analyses and Systemic Reviews of Androgenic Alopecia and Treatments

in Research/Science 14 upvotes 4 years ago

Evidence-based treatments for androgenic alopecia, such as minoxidil, finasteride, low-level laser light therapy, dutasteride, platelet-rich plasma, and topical ketoconazole. It discusses the efficacy, safety, and mechanism of action of these treatments, as well as future developments in understanding this polygenic condition.

community Kintor Has Completed Enrollment in Phase II Clinical Trial of KX-826 (Pyrilutamide) for Treatment of Male AGA Patients in the US

in Update 23 upvotes 2 years ago

KX-826 (Pyrilutamide) being tested in the US for hair loss treatment and that they have found enough people to participate in phase II clinical trials. Other treatments discussed are Minoxidil, finasteride, and RU58841.

community Hair Loss Drugs Ranked in Order of Efficacy

in Research/Science 67 upvotes 1 year ago

Dutasteride is likely the most effective treatment for male pattern baldness, followed by finasteride and minoxidil in various forms and dosages. Users discuss personal experiences, dosages, and potential side effects, with some considering combining treatments for better results.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 4 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community First patient dosed with Pyrilutamide (Kintor) Phase III

in Research/Science 200 upvotes 2 years ago

First patient dosed with Pyrilutamide (Kintor) Phase III for hair loss treatment. Pyrilutamide differs from approved treatments as it competes with DHT to bind hair follicles, potentially reducing side effects.

community Ultrax Labs Hair Surge Caffeine Hair Loss Hair Growth Stimulating Shampoo - For real?

in Question 3 upvotes 8 years ago

The conversation is about the effectiveness of Ultrax Labs Hair Surge Caffeine Hair Loss Hair Growth Stimulating Shampoo, with the original poster questioning if the positive reviews are genuine or not. No specific treatments were discussed.

community Homemade topical spironolactone

in Research/Science 26 upvotes 2 years ago

The potential effectiveness of homemade topical spironolactone in treating hair loss, with studies suggesting it is more effective than finasteride and even minoxidil when used as monotherapy. The conversation also mentions that other anti-androgens are being developed which may soon hit the market.

community Spironolactone for 11 years, finasteride for almost 5 years, started oral minoxidil in November 😢 ended oral contraceptive in Dec.

in Progress Pictures 224 upvotes 8 months ago

A user shared their 11-year experience with spironolactone and nearly 5 years with finasteride for hair loss, recently adding oral minoxidil and stopping birth control. Various treatments were discussed, including organic options, checking for underlying health issues, considering dutasteride, and the potential role of progesterone in hair loss.

community What is worth dissolving in topical minoxidil solution?

in Treatment 3 upvotes 3 months ago

Switching from minoxidil foam to topical solution and considering adding caffeine, melatonin, or cetirizine. Currently using 2.5mg oral minoxidil and 1mg oral finasteride, planning to ask for 0.5mg oral dutasteride and 5mg oral minoxidil.

community Estimate of GT20029 on the grey market?

in Technology 9 upvotes 1 year ago

The conversation is about when GT20029, a hair loss treatment, might be available on the grey market, with users discussing the challenges of compounding it and speculating it might be available after phase 2 results, similar to pyri. Specific treatments mentioned are pyri, RU58841, and GT20029.

community The no BS guide to saving your hair without finasteride (improvement in 90% of patients in the study) with a low side effect profile or improvement in 100% of patients but a higher side effect profile and increased dosage. The future is here?

in Minoxidil 92 upvotes 4 years ago

Hair loss treatments, specifically the use of oral minoxidil in combination with micro-needling. Oral minoxidil has been found to improve hair density in 90% of patients with a low side effect profile, but using 5mg per day can result in higher side effects including hypertrichosis and edema. Other treatments mentioned include finasteride and RU58841.

community Considering giving a laser comb a shot. Here’s a summary of my research on the subject.

8 upvotes 8 years ago

Considering adding Low Level Laser Therapy (LLLT) to a hair loss prevention regimen; discussing the effectiveness of LLLT, and evaluating double-blind random-controlled trials that have been conducted on laser combs.

community 2020 Hair and Scalp Treatments: A Clinical Guide (in Depth 350 Page Guide)

in Treatment 64 upvotes 4 years ago

Treatments for hair loss, including topical immunotherapy, regenerative treatments, laser and light-based therapies, oral supplements, intralesional steroids, and new drugs like finasteride and minoxidil.

community 2.5 months topical minoxidil Progress

in Progress Pictures 440 upvotes 10 months ago

The conversation is about a user's hair regrowth after 2.5 months using topical minoxidil. Some suggest adding finasteride for long-term results, while others share their experiences with side effects or alternative treatments like dermarolling and dietary improvements.

community Anyone else realize how many younger guys are balding?

in Chat 262 upvotes 2 months ago

Many younger men are experiencing hair loss due to genetics, diet, stress, and lifestyle changes. Treatments like finasteride and minoxidil are mentioned, with some users noting improvements.

community FINASTRIDE and switch to DUTASTRIDE, my experience

in Progress Pictures 138 upvotes 3 months ago

The user shared their experience with Finasteride and Dutasteride for hair loss. They initially had success with Finasteride but switched to Dutasteride after experiencing shedding, which continued, and are now considering a hair transplant.

community Is topical finasteride as effective as oral finasteride?

in Finasteride/Dutasteride 6 upvotes 5 months ago

Topical finasteride is almost as effective as oral finasteride with fewer side effects. Users are considering between oral and topical finasteride for hair loss treatment.

community Micro needling 25 days progress. I’ve been on fin and min for 6 months but micro needling has done SO much more to actually restore my hairline

in Progress Pictures 569 upvotes 9 months ago

A user shared a 25-day progress picture showing significant hairline restoration attributed to microneedling, in addition to using minoxidil and finasteride for 6 months. Other users discussed needle length, frequency, and whether the effects of microneedling are permanent.

community 4 months progress / dut 0.5mg + topical min

in Progress Pictures 108 upvotes 10 months ago

The conversation is about someone's 4-month hair regrowth progress using 0.5mg dutasteride and topical minoxidil. Another person is inspired and is using 5mg finasteride and 5% minoxidil topically twice daily, hoping for similar results.

community Why nobody uses 0.25% (2.5mg/ml)?

in Treatment 66 upvotes 11 months ago

The conversation is about the effectiveness of 0.25% topical finasteride compared to other concentrations and forms. Users discuss its potential for better scalp DHT reduction and fewer side effects, with some preferring topical over oral treatments.

community Exploring Bryan Johnson's Hair Routine In Detail

in Research/Science 64 upvotes 11 months ago

Bryan Johnson uses a custom hair loss treatment that includes topical finasteride, minoxidil, azelaic acid, diclofenac, tea tree oil, rosemary oil, ginkgo biloba, biotin, and melatonin, which have shown varying degrees of effectiveness with minimal side effects. He also undergoes PRP and laser therapy, and has tried dutasteride mesotherapy.

community 15ish months results. Fin plus Min

in Progress Pictures 481 upvotes 1 year ago

CraigMeyerShirtPants used oral finasteride for 15 months and topical minoxidil for 6 months, seeing significant hair growth after cutting hair 4 months ago. Users congratulated and asked about age, brand, and side effects.

community Any success stories switching from finasteride to dutasteride?

in Finasteride/Dutasteride 36 upvotes 1 year ago

Switching from finasteride to dutasteride for treating hair loss, with reports of improved regrowth and little to no side effects.