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Did you mean Major Histocompatibility Complex class I?

GlossaryMHC class I (Major Histocompatibility Complex class I)

present protein fragments to cytotoxic T cells for immune response

MHC class I, or Major Histocompatibility Complex class I, are molecules found on the surface of almost all nucleated cells in the body. They play a crucial role in the immune system by presenting small fragments of proteins (peptides) from inside the cell to cytotoxic T cells. This helps the immune system recognize and destroy infected or cancerous cells.

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community Major body hair loss from Finasteride (Also, just started oral minoxidil this week.)

in Finasteride/Dutasteride 6 upvotes 1 year ago

User experienced significant body hair loss from Finasteride and started oral Minoxidil to address crown thinning. Their current regimen includes 1mg Finasteride, 2.5mg Minoxidil, Biotin, Vitamin D, Zinc, Iron, and ketoconazole shampoo.

community GT20029 & KX826 Major Updates from Kintor.

in Research/Science 98 upvotes 2 weeks ago

KX826 shows promise as a hair loss treatment with a 10% increase in hair count, but concerns about Kintor's marketing practices and the systemic effects of treatments like GT20029 and RU58841 remain. Users express skepticism and hope, with some preferring traditional treatments like finasteride and minoxidil.

community Interesting article links major MPB theories to western diet (and life-style)

in Research/Science 56 upvotes 1 month ago

Poor diet and lifestyle contribute to male pattern baldness. Treatments like Minoxidil, dietary changes, and lifestyle adjustments may help slow hair loss.

community RU58841 and some major questions?

in Treatment 7 upvotes 11 months ago

A user is asking about the effectiveness and dosage of RU58841 for hair loss, comparing it to Minoxidil and discussing its long-term use alongside Finasteride. They plan to use RU58841 and Finasteride for several years before potentially switching to GT20029.

community Blood test showing major reduction in DHT on finasteride results

in Finasteride/Dutasteride 14 upvotes 2 years ago

A user reported a significant reduction in DHT levels after 3 months of taking 1mg/day oral finasteride, along with using minoxidil foam, microneedling, and Nutrafol vitamins. They hope this will lead to hair growth and less shedding.

community Dutasteride SAVES your hair follicles: MAJOR BS on people who say it destroyed their hair permanently.

in Finasteride/Dutasteride 156 upvotes 1 year ago

The conversation discusses the effectiveness of hair loss treatments, specifically finasteride and dutasteride. The conclusion is that dutasteride significantly reduces DHT levels and may be more effective than finasteride for long-term hair retention, with some users reporting personal experiences and side effects.

community 22 years since the last major development

in Technology 52 upvotes 3 years ago

The conversation discusses the lack of significant advancements in hair loss treatments since the introduction of finasteride 22 years ago, with many expressing frustration over the failure of new projects and skepticism about future developments. Some users mention hair transplants and other potential alternatives like Alfatradiol and Fluridil, but acknowledge finasteride's dominance in the market due to its effectiveness and affordability.

community I'm 27 f with major hairloss, should my dermatologist be doing more?

in Question 3 upvotes 6 years ago

A 27-year-old woman experiencing significant hair loss is using spironolactone, Nizoral shampoo, and betamethasone valerate. She questions the effectiveness of these treatments and whether she should seek another dermatologist.

community 24 M diffuser, 3 months major progress

in Update 7 upvotes 6 years ago

A 24-year-old male saw major hair regrowth progress in 3 months using Nizoral, minoxidil, finasteride, vitamins, and dermarolling. After 7 months, he switched to liquid minoxidil, oral finasteride, and stopped dermarolling.

community Acute shedding episodes. Had telogen effluvium last year. Remission for a few months(thought I was over the shedding stuff 🥲). Now if I have any major stress days, THAT day I get a major shed and a few days after.

in Female 3 upvotes 2 months ago

The user experiences immediate hair shedding linked to stress, unlike typical telogen effluvium, and is seeking answers. A suggestion was made to use spironolactone and topical minoxidil to address potential DHT-related shedding.

community I am not losing my hair (yet) and do not think I will soon, but I am a pre medicine major who has an obsession over stem cells and want to share something with you all. Your future is brighter than you think.

19 upvotes 7 years ago

User hoodoomoovoo discusses their interest in stem cell research and its potential for hair loss treatment. They share links to studies and mention ongoing trials, expressing optimism for a future solution to hair loss.

community Hairfall is happening after 6 month of treatment and doctor doesn't give a F

in Finasteride/Dutasteride 3 upvotes 5 months ago

User experienced major hair fall after six months of using minoxidil, finasteride, and dutasteride. Replies suggest the hair shedding is normal and will improve over time.

community First 3 months on Propecia

6 upvotes 9 years ago

The user experienced no major negative symptoms from Propecia but noted ball throbbing and emotional inertia. They also used Minoxidil and observed increased focus and prolonged moods.

community 4 month Progress picture(finasteride and minoxidil combo)

in Progress Pictures 279 upvotes 1 month ago

A user reported significant hair regrowth after 4 months using finasteride and minoxidil, with no major side effects. They are considering oral minoxidil and use microneedling and ketoconazole shampoo.

community My Testosterone results before and after Finasteride

in Update 146 upvotes 3 years ago

Finasteride significantly increased testosterone levels for the user, with no major side effects except watery semen, which was resolved with zinc supplements. The user's hairline stopped receding and slightly improved.

community 1 Year update with a lot of pics (you have been warned)

in Update 55 upvotes 7 years ago

The user has been taking finasteride for a year, experiencing no major side effects except watery semen, and has noticed healthier, thicker hair with some regrowth but mostly maintenance. They also use Nizoral for dandruff, take supplements like D3 and fish oil, and plan to continue finasteride while waiting for new treatments.

community I think Progress 6 months mark what do you think guys

in Progress Pictures 122 upvotes 2 weeks ago

The user experienced significant hair regrowth and reduced shedding after using finasteride, dutasteride, and topical minoxidil for six months, with no major side effects. The user emphasizes the importance of tracking progress and plans to continue the treatment indefinitely.

community 31, Month 1 vs month 3 of treatment, Min 5% topical 2x daily, Fin oral 0.625mg 1x daily

in Progress Pictures 59 upvotes 3 weeks ago

A 31-year-old experienced significant hair regrowth using Minoxidil 5% topical twice daily and Finasteride 0.625mg daily, with additional microneedling. The user reported initial shedding, improved hair thickness, and no major side effects, impressing their dermatologist with the results.

community 1.5yrs Fin 5m Min.. wow it was bad

in Progress Pictures 250 upvotes 1 month ago

The user experienced significant hair improvement using 1mg finasteride and 2.5mg oral minoxidil daily, with most gains attributed to finasteride. They also stopped using topical treatments due to scalp psoriasis and reported no major side effects.

community A long journey but it’s working. I had hardly any hair left.

in Progress Pictures 2326 upvotes 2 months ago

The user experienced significant hair regrowth using 5% topical minoxidil twice daily and 1mg oral finasteride once daily over a year. They reported no major side effects, only slightly less chest hair.

community 3 month progress on min + fin capsule

in Is this regrowth? 400 upvotes 2 months ago

The user experienced significant hair regrowth in three months using a capsule containing minoxidil and finasteride. They reported no major side effects and plan to continue the treatment until their late 20s.

community 2 month progress pictures / July 2024 - September 2024 (promising results full backstory and routine in description)

in Progress Pictures 81 upvotes 3 months ago

A user shared their 2-month hair regrowth progress using 1mg finasteride daily, 5% minoxidil once daily, 1% nizoral shampoo twice a week, and weekly derma stamping. They reported significant improvement and no major side effects, with plans to consider dutasteride if needed.

community 2 Years Results - 0.5mg Fin Only.

in Progress Pictures 442 upvotes 6 months ago

A user shared their 2-year results using only 0.5mg finasteride for hair loss, noting improvement after 8-10 months and no major shedding or side effects. They are 34 years old and have avoided using Minoxidil.

community How important is microneedling (dermarolling)?

in Microneedling 9 upvotes 7 months ago

A user has been using oral finasteride and minoxidil without significant hair regrowth and is questioning the effectiveness of adding microneedling to their routine. Another user suggests microneedling can help with topical treatments but doesn't see it as a major factor in improving hair loss.

community 6 months only finasteride 1.25 mg

in Progress Pictures 1367 upvotes 8 months ago

After six months on 1.25 mg of finasteride, a user reports significant hair regrowth with no major shedding and uses a local brand of the medication. Some users inquire about side effects and brand differences, while others share their own experiences and concerns about hair loss treatment.

community Hypertrichosis Photos from Oral Minoxidil

in Progress Pictures 266 upvotes 10 months ago

A user shared their experience with oral minoxidil and finasteride for hair loss, taking 7.5mg of minoxidil and experiencing excessive hair growth all over their body without major side effects. Some users suggested lower doses for safety, while others shared their own experiences with hair growth in different areas and side effects.

community My barber noticed my progress 😁

in Update 209 upvotes 10 months ago

A user's barber noticed significant improvement in their hair thickness after they started using 2.5mg Minoxidil since August 2023 and 1mg Finasteride daily since September 2023. The user has experienced some headaches when missing Minoxidil doses but has not noticed major side effects.

community Kintor has released an investor relations memo regarding Chinese Phase III trials for Pyrilutamide

in Update 50 upvotes 1 year ago

Kintor's Pyrilutamide (KX-826) showed hair growth in Chinese Phase III trials but did not significantly outperform placebo. The treatment was safe with no major adverse reactions reported.

community Progress: 0.5mg finasteride + 2.5 mg oral minoxidil

in Progress Pictures 431 upvotes 1 year ago

This user uses a combination of finasteride and oral minoxidil to treat hair loss, and reports that the treatment has had an impact on his growth without any major side effects. He also shares advice on how to obtain the necessary medications in certain countries.

community Why Is Only Tressless Talking About Verteporfin? Healing Wounds With Zero Scarring Has Gargantuan Implications For All of Medicine. So What Gives?

in Research/Science 19 upvotes 2 years ago

The potential of verteporfin to heal wounds without scarring; however, despite its promising preclinical trials and coverage from a major media outlet, there is still no official clinical trial result and the drug has only garnered attention from hair loss communities.