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Glossary Interleukins

proteins that help cells communicate in the immune system

Interleukins are a group of proteins that play a crucial role in the immune system by facilitating communication between cells. They help regulate inflammation, immune responses, and the development of white blood cells. For example, certain interleukins can promote the growth of T-cells, which are essential for fighting infections, while others can trigger inflammation to help the body respond to injury or infection.

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community NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

14 upvotes 2 years ago

NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.

community IGF-1 and Peptides? Miracle molecule waiting to be found

10 upvotes 1 year ago

The conversation discusses potential hair loss treatments focusing on stimulating IGF-1 at the follicle level using growth-factor cocktails and engineered peptides, such as Acetyl Tetrapeptide-3, Copper Tripeptide-1, Oligopeptide-20, Thymosin-β4, and Palmitoyl Tetrapeptide-7. It suggests that device-assisted delivery methods like microneedling may enhance effectiveness.

community IGE Hair Loss and Miniaturization

in Chat 3 upvotes 1 year ago

A 23-year-old male is experiencing diffuse hair loss and miniaturization, possibly due to high IGE levels after using tofacitinib. He seeks advice and has not yet consulted a dermatologist.

community What if DHT is not the vilan.

13 upvotes 5 years ago

Hair loss may be influenced more by inflammation, microbiome imbalances, and gut health than DHT. Treatments discussed include minoxidil, finasteride, RU58841, fecal microbiota transplants, and JAK inhibitors.

community Collagen peptides(powder) i highly recommend

7 upvotes 1 year ago

Collagen peptides are recommended for hair and skin benefits, with users noting improvements in hair and skin health. However, evidence on their effectiveness for hair growth is inconclusive.

community MCL1 does anyone knows anthying about it

in Research/Science 9 upvotes 1 year ago

MCL-1 protein may help maintain hair follicles in the growth phase and prevent miniaturization. There is interest in experimental treatments like exosomes, peptides, or stem cell serums to upregulate MCL-1 for hair loss, especially for those not using minoxidil or finasteride.

community Hives/Rash from Kx 826 Pyrilutamide???

1 upvotes 1 year ago

OP developed hives after using Kx 826 (Pyrilutamide) 1% twice daily for 3 weeks. The hives appeared on the arms, chest, and groin area.

community Scalp Inflammation Beyond Psoriasis: A Hidden Player in Hair Thinning

in Technology 54 upvotes 4 months ago

Scalp inflammation may contribute to hair thinning, with treatments like ketoconazole shampoo potentially helping by reducing inflammation. Some users report that DHT blockers and other treatments like finasteride, minoxidil, and RU58841 can alleviate symptoms associated with inflammation.

community Cetirizine (Zyrtec), to help with inflammation.

3 upvotes 2 years ago

The user experiences an itchy scalp and finds relief using shampoo and Zyrtec, which helps with inflammation. They are unsure if the issue is related to histamines or seborrheic dermatitis.

community Peptide Therapy -> GHK-CU, ZN-Thumulin, PTD-DBM

4 upvotes 2 years ago

The conversation is about the use of peptide therapies for hair loss, specifically GHK-CU, ZN-Thymulin, and PTD-DBM. The user is seeking feedback on the effectiveness of these treatments from those who have tried them.

community Winlevi Clascoterone- resultssss

4 upvotes 2 days ago

The conversation is about using Winlevi Clascoterone cream for hair loss. The user is considering adding it to their routine, which includes a topical hair growth serum, and is seeking feedback on its effectiveness.

community Has anyone tried thymosin beta 4 injections for hair growth?

7 upvotes 1 year ago

Thymosin beta 4 injections for hair growth. Other treatments mentioned include Minoxidil, finasteride, and RU58841.

community IGFBP‐rP1 is a potential therapeutic target in androgenic alopecia

in Research/Science 13 upvotes 1 year ago

IGFBP‐rP1 shows potential for treating androgenic alopecia by influencing hair cycle transitions. Increasing IGF-1 levels may have similar effects to Minoxidil and 5-AR inhibitors in reducing hair loss.

community Elastin based peptides help reduce wrinkles. Can they help the scalp too?

14 upvotes 5 months ago

Elastin-based peptides may help reduce wrinkles and could potentially benefit the scalp. The conversation suggests using them with hyaluronic acid gel to improve scalp health and reduce hair fall.

community Kintors interim report from 9-2-24 for everyone whos interested

32 upvotes 2 years ago

Kintor plans to release pyrilutamide foam and a plant-based Koshine by year-end, with GT20029 progressing in their pipeline. Users are pleased about the absence of propylene glycol (PG) in the new products.

community Got my Oleic fatty acid they used in Korean study. Fuck you mice!

247 upvotes 7 months ago

Oleic acid and microneedling are being explored for hair regrowth, but results are mixed. Addressing DHT and fibrosis is crucial, with treatments like finasteride, minoxidil, and scalp massage also discussed.

community An arthritis drug that can be used for Alopecia.

5 upvotes 4 years ago

An arthritis drug, baricitinib, is discussed as a potential treatment for autoimmune alopecia, not androgenetic alopecia. Ritlecitinib is also mentioned as a possible treatment for scarring alopecia.

community Women complaining of bad effects from Winlevi (Clascoterone 1%)

11 upvotes 9 months ago

Women experienced severe reactions, including Topical Steroid Withdrawal (TSW), from using Winlevi (Clascoterone 1%) on their faces. Concerns were raised about the potential risks of higher concentrations, especially for hair loss treatment.

community Peptides? Men's Journal article.

9 upvotes 2 years ago

The conversation is about the effectiveness of peptides for hair loss and the user considering using GHK-Cu, CJC-1295, and BPC-157 for treatment.

community ASCEplus HRLV Exosomes with microneedling

1 upvotes 2 years ago

The discussion is about using ASCEplus HRLB exosomes for hair loss treatment, which combines 10 billion exosomes with growth factors, nutrients, biotin, and copper tripeptide. The treatment is expensive and typically administered via scalp injections, but in Europe, it's done with microneedling.

community Injectable and biofunctionalized fibrin hydrogels co-embedded with stem cells induce hair follicle genesis.

5 upvotes 3 years ago

Fibrin-based hydrogels support stem cells for hair follicle regeneration, showing promise for treating alopecia and wound healing. They enhance cell viability, maintain stemness, and promote hair and tissue regeneration without teratoma formation.

community Gut microbiome imbalances linked to scalp inflammation and hair follicle impact

in Technology 243 upvotes 4 months ago

Gut microbiome imbalances can cause scalp inflammation and affect hair follicles, potentially leading to hair loss. Treatments include finasteride, peptides like BPC-157, TB-500, KPV, and lifestyle changes such as diet and exercise.

community Injectable and biofunctionalized fibrin hydrogels co-embedded with stem cells induce hair follicle genesis.

11 upvotes 3 years ago

Fibrin hydrogels, when combined with stem cells, can induce hair follicle regeneration and show potential for treating alopecia. The study demonstrated successful hair growth in mice without adverse effects.

community Scalp inflammation let’s talk about it?

in Chat 11 upvotes 1 year ago

Scalp inflammation can cause hair thinning and may be related to diet, infections, or conditions like psoriasis. Treatments suggested include using Nizoral shampoo and checking vitamin levels.

community Hair Loss & Lipids: Why you have sebderm, folliculitis, LPP, inflammation, etc...

131 upvotes 1 year ago

Excess sebum rich in cholesterol and triglycerides can lead to hair loss through inflammation, with treatments like Ciclopirox shampoo, Benzoyl Peroxide shampoo, and Clindamycin gel recommended for managing conditions like seborrheic dermatitis and folliculitis. Pioglitazone is suggested for Lichen Planopilaris, while Omega-3s and reducing processed foods may improve sebum quality, though genetic factors play a significant role.

community "14" peptides will be able to be legally compounded by US pharmacies soon, according to RFK Jr. podcast comments.

in Product 52 upvotes 6 months ago

Peptides are being discussed for potential hair loss treatments, but most are not proven effective for this purpose. Minoxidil and finasteride are mentioned as more reliable options for hair growth.

community Xeljanz medication for alopecia universalis?

4 upvotes 2 months ago

A person with alopecia universalis is considering using Xeljanz but is advised that Olumiant is more effective for their condition. They are under a dermatologist's care and should expect gradual progress, as follicles dormant for 20 years are challenging to reactivate.

community Winlevi (clascoterone 1%) anyone trying it

in Treatment 2 upvotes 8 months ago

Winlevi (clascoterone 1%) is being discussed as a potential hair loss treatment. Users are considering its use despite concerns about its delivery method.

community Estradiol mesotherapy / idea feedback

5 upvotes 1 year ago

The conversation discusses using estradiol mesotherapy to replicate hormone replacement therapy results while minimizing systemic exposure. It also covers the use of Spironolactone cream, which reportedly has no systemic side effects, and the potential risks of using bicalutamide and Spironolactone in men.

community Rejux-3x - the copper peptide combo that tressless overlooks.

1 upvotes 5 months ago

Rejuv-3X, a topical blend with GHK-Cu, AHK-Cu, and JXL-089, is used for hair loss, offering a targeted option without finasteride's side effects. The user plans to combine it with microneedling for enhanced results.