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GlossaryImmune-Related Pathways

series of immune system interactions responding to threats

Immune-related pathways are the series of interactions and processes within the body that involve the immune system's response to threats like infections, diseases, or even malfunctioning cells. These pathways include the activation of immune cells, the release of signaling molecules, and the coordination of various immune responses to protect the body. Understanding these pathways is crucial for developing treatments for autoimmune diseases, where the immune system mistakenly attacks the body's own tissues, such as in alopecia areata.

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community dutasteride 9 months, nonstop hair loss

in Finasteride/Dutasteride 31 upvotes 2 years ago

Experiencing continual nonstop hair loss despite using dutasteride for 9 months, and the possible causes behind it being discussed such as nutritional deficiencies, elevated cortisol, vitamin D deficiency or other problems. Other solutions such as minoxidil and finasteride have been suggested.

community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

in Treatment 100 upvotes 4 years ago

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 43 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Dutasteride SAVES your hair follicles: MAJOR BS on people who say it destroyed their hair permanently.

in Finasteride/Dutasteride 160 upvotes 7 months ago

The conversation discusses the effectiveness of hair loss treatments, specifically finasteride and dutasteride. The conclusion is that dutasteride significantly reduces DHT levels and may be more effective than finasteride for long-term hair retention, with some users reporting personal experiences and side effects.

community How is it that golden era bodybuilders kept their hair while blasting gear while in the modern era most are bald? I’m convinced there’s something in our food and water causing MPB to speed up

in Satire 725 upvotes 1 year ago

The conversation is about the difference in hair loss between bodybuilders in the "Golden Era" and modern bodybuilders. Some users speculate that factors such as the types and doses of steroids used, genetics, diet, microplastics, and overall health may contribute to hair loss. Hair loss prevention medication and transplants are mentioned as potential treatments.

community I think it’s time to drop Pyrilutamide at this point?….

in Update 31 upvotes 1 year ago

A user who has been using Pyrilutamide for 5 months with no results, and other users suggesting they switch to RU58841 or stick to their treatment plan for at least one year.

community Got a microscope camera. Here’s the difference between healthy and miniaturized hair

in Progress Pictures 492 upvotes 2 years ago

A user who shared progress pictures of their scalp using a microscope camera, demonstrating the difference between healthy and miniaturized hair. Various explanations for the cause of this were discussed, such as DHT build-up in scalp sebum causing an autoimmune response leading to inflammation and eventual hair loss, with some suggesting a do-it-yourself treatment involving adding ascorbic acid powder to shampoo.

community Embraced baldness. Time to leave this subreddit

in Chat 813 upvotes 2 days ago

A user shared their positive experience of embracing baldness after years of trying treatments like Minoxidil and finasteride. They found happiness and confidence by shaving their head, despite some social challenges, and encouraged others to focus on their attitude and seek therapy if needed.

community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 448 upvotes 3 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

community WOMEN on Spironolactone – experiences?

6 upvotes 8 years ago

Hair loss treatments discussed: Minoxidil, Finasteride, RU58841, and Spironolactone. Woman with androgenetic alopecia and alopecia areata shares experience using Spironolactone.

community It’s crazy how it’s 2018 and the only hair loss treatments we have feature undesirable side effects and/or aren’t even effective for many people.

136 upvotes 6 years ago

Hair loss treatments, including minoxidil, dermarolling, finasteride, dutasteride, hair transplants, hair systems, and shaving the head. The conversation covers various opinions on these treatments and mentions possible side effects as well as alternatives like wigs, vitamins, and lifestyle changes. The post expresses disappointment that there has been no major breakthrough in the field of hair loss treatments despite decades of research.

community Zyrtec (Cetirizine) antihistamine for hair growth compared to Minoxidil NIH study

in Minoxidil 38 upvotes 1 year ago

The conversation discusses the potential of topical cetirizine (Zyrtec) for hair growth in comparison to minoxidil, noting cetirizine's ability to reduce prostaglandin D2, which inhibits hair growth. Users share mixed experiences with cetirizine for allergies and scalp health, and there's a mention of the risk of dementia with long-term antihistamine use.

community Is itching related to hair loss?

in Treatment 54 upvotes 1 year ago

Hair loss, which is sometimes accompanied by itching. Treatments discussed include Minoxidil, finasteride, RU58841 and ketocazole shampoo.

community Sharing what worked for me (PCOS related hair loss)

in Female 33 upvotes 7 months ago

A user with PCOS experienced hair loss and found success using a triple dose of O.N.E Omega by Pure Encapsulations after discovering low Omega fatty acids. Biotin provided minimal improvement, but the Omega supplement significantly restored hair.

community Hope Medicine announces HMI-115 phase II clinical trial for androgenetic alopecia in China

in Research/Science 59 upvotes 1 year ago

Hope Medicine's announcement of the HMI-115 Phase II clinical trial for androgenetic alopecia in China; other related trials have been conducted or are ongoing in different countries, including Australia, US, and Europe. There is speculation that the product may be accepted across borders without additional testing.

community Rare Non responder to Finasteride, Dutasteride, and oral minoxidil

in Minoxidil 78 upvotes 5 months ago

A user did not respond to finasteride, dutasteride, and oral minoxidil for hair loss after four years of treatment and is considering scalp micropigmentation (SMP). Other users suggest the hair loss pattern may indicate alopecia areata and recommend seeing a dermatologist.

community I hate it when people write off your hairloss info because “you’re not a doctor.”

in Treatment 78 upvotes 10 months ago

A user shared their frustration about their cousin's refusal to take their advice on using finasteride for aggressive hair loss, despite the cousin's desperation and current use of minoxidil and consideration of PRP injections. The user, who has done extensive research, suggested the cousin needs a 5ar inhibitor, but the cousin dismisses the advice because the user isn't a doctor.

community HELP! Hair transplant for me (with pics) ?

in Transplants 8 upvotes 2 years ago

User tried various hair loss treatments with side effects. Seeks advice on hair transplant without maintenance drug.

community Effectiveness and Safety of Botulinum Toxin Type A in the Treatment of Androgenetic Alopecia

in Research/Science 7 upvotes 3 years ago

Botox injections increase hair density in patients with androgenetic alopecia. Combining Botox with finasteride yields even better results.

community Autoimmune disease and balding

in Update 12 upvotes 2 months ago

A user diagnosed with Crohn's disease is concerned it might contribute to balding. They have been using keto shampoo, finasteride, and oral minoxidil, which improved their hair but not significantly.

community 2.5 Years Progress FUE Hair Transplant Turkey!

in Progress Pictures 633 upvotes 1 year ago

The post is about a user sharing their hair transplant results after 2.5 years. They did not use any medications like finasteride or minoxidil.

community Is hair thinning or loss associated with pain?

in Research/Science 6 upvotes 1 year ago

Hair thinning/loss associated with burning scalp pain. Finasteride helped relieve "DHT itch" for one person.

community I am a dermatologist with a clinical interest in alopecia. AMA

in Will treatment work for me? 1 year ago

In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

community Faced my fear and made a doctor appointment

in Finasteride/Dutasteride 51 upvotes 2 years ago

Facing fears and making a doctor appointment to get more info on individual hair loss cases, as well as the discussion of potential treatments such as Finasteride/Dutasteride, Minoxidil, or RU58841.

community 2 weeks on Oral Minoxidil (loniten). 1.25mg/day

in Minoxidil 10 upvotes 3 years ago

The user has been taking oral Minoxidil (1.25mg/day) for two weeks to treat hair loss, has experienced no side effects, and plans to increase the dose to 2.5mg/day after another two weeks. They are also monitoring their blood pressure and have not noticed any negative interactions with their pre-workout supplements.

community How I started reversing Male Pattern Baldness naturally ?

in Question 6 upvotes 7 years ago

The user reversed male pattern baldness using a pro-thyroid diet, lifestyle changes, and scalp stimulation exercises, without Minoxidil or Finasteride. They reported reduced dandruff, itchiness, oiliness, and experienced hair regrowth and thickening over 15 months.

community Still getting DHT itch after 6 months on Finasteride, should I swap to Dutasteride?

in Chat 6 upvotes 3 weeks ago

User is experiencing scalp itch and hair loss despite using Nizoral, Minoxidil, derma rolling, and Finasteride for 6 months. They are considering switching to Dutasteride.

community MY 6 MONTH TRANSFORMATION PROGRESS

in Progress Pictures 204 upvotes 1 month ago

A 23-year-old male shared his 6-month hair transformation using Dutasteride, oral Minoxidil, ketoconazole shampoo, vitamin D, gym, cardio, and dermastamping. He reported significant hair maintenance and no side effects.

community Do I get a hair transplant at 22?

in Transplants 11 upvotes 4 months ago

A user has been using dutasteride and oral minoxidil for hair loss with no change and is considering a hair transplant at age 22. Replies suggest that a transplant is possible if DHT blockers like finasteride are continued, and another user shared a positive personal experience with a transplant at age 20.

community 0.5mg Dutasteride promotes more “regrowth” than 5mg oral Minoxidil

in Research/Science 119 upvotes 6 months ago

Dutasteride promotes more hair regrowth than Minoxidil. Users discuss combining treatments for better results and share personal experiences with side effects.