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GlossaryDermal Papilla Cells

specialized cells at hair follicle base crucial for hair growth

Dermal Papilla Cells (DPCs) are specialized cells located at the base of hair follicles. They play a crucial role in hair growth and regeneration by interacting with surrounding cells to regulate the hair growth cycle. These cells are essential for the formation of new hair follicles and are a key focus in research on hair loss treatments and regenerative medicine.

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community DIY treatment... Shedding completely stopped after 1.5 yrs

Fluid_Support1292 in Treatment 248 upvotes 3 years ago

Vitamin C mixed with shampoo stopped shedding and promoted hair regrowth after 1.5 years. Both the person and their wife experienced significant hair loss reduction with this method.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

nkrata in Research 830 upvotes 6 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community COMPLETE OVERVIEW of the Treatment of androgenetic alopecia in men

Honor_Bound 26 upvotes 10 years ago

Male androgenetic alopecia is commonly treated with topical minoxidil and oral finasteride, both requiring continuous use. Other options include hair restoration surgery, dutasteride, light therapy, and camouflaging agents.

community Being Safe on Oral Minoxidil: tl;dr on the literature.

noeyys in Research/Science 49 upvotes 1 month ago

Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.

community 18 months. Dutasteride, RU58841, Minoxidil, Microneedling, Nizoral, T/GEL

manlycoffee in Progress Pictures 167 upvotes 4 years ago

A 28 year old man's 18-month journey to treat his hair loss with Dutasteride, RU58841, Minoxidil, Microneedling, Nizoral and T/GEL. He experienced some side effects along the way, including translucent semen and scalp less oily.

community Possible topical option for preventing BDNF-related hair loss

Wearethemusicmaker in Research/Science 7 upvotes 1 year ago

The conversation discusses hair loss linked to BDNF-increasing nootropics like Semax and Lions Mane. Suggested topical treatments include capsaicin, beta-glucan, and ginseng to counteract TGF-B activation.

community redensyl - follicle stem cell activator any experiences?

ad0rn1t3 in Question 8 upvotes 7 years ago

A Swiss product called Redensyl, which is supposed to target hair follicle stem cells and has recently been marketed in Europe. The post inquires if anyone has had any experience with the product.

community ladies and gentlmen, vitamin E is your hair follicles second best friend

milofam in Treatment 51 upvotes 2 years ago

Vitamin E is suggested as beneficial for hair follicles. Some users question the dosage and effectiveness, while others share positive experiences with vitamins.

community CRISPR Is Curing People Right Now. Genetic Hair Loss is Next?

noeyys in Technology 107 upvotes 4 months ago

CRISPR shows promise for treating hair loss by targeting specific genes. Current treatments include Minoxidil and finasteride, but CRISPR could offer a more precise solution, though it is still expensive and in early stages.

community New and Interesting HairLoss Studies/Papers/Reviews

TerpsandCaicos in Treatment 41 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Taking Charge of Your Hair: The "Big 3 Stack" Explained for 2023

RadiantBlissUK in Research/Science 129 upvotes 1 year ago

The "Big 3 Stack" for hair loss treatment, which includes Minoxidil for hair density improvement, Ketoconazole shampoo for enhancing hair volume and thickness, and Finasteride for blocking hair loss causing hormones. Microneedling can boost Minoxidil's effects.

community Extreme hair and beard growth from Stemoxydine. Big 3 + 1?

VonHilsenburgEverc in Product 23 upvotes 4 years ago

Using a combination of Stemoxydine, minoxidil, dutasteride, and keto shampoo to achieve extreme hair and beard growth. The user has experienced positive results with terminal hairs at the hairline and an increase in density to their stubble after several weeks of use.

community Update: 16 months deep - big 3

Interesting-Art-2447 in Progress Pictures 407 upvotes 1 year ago

The user has seen positive results after 16 months of using topical Finasteride/Minoxidil, microneedling weekly, and Tretinoin for hair loss. There are no reported side effects, and the user advises that the effectiveness of microneedling depends on the pressure applied.

community Epibiotech will now offer off-the-shelf allogeneic hair multiplication treatment in South Korea

mirsat2016 in Research/Science 78 upvotes 2 years ago

Epibiotech will offer off-the-shelf allogeneic hair multiplication treatment in South Korea, using dermal papilla cells from donors to grow hair in balding areas. This method is cheaper and less invasive than traditional hair transplants.

community HairClone: Good info from their site

usual-performance in Technology 10 upvotes 2 years ago

HairClone aims to rejuvenate miniaturizing hair follicles through follicle banking and cell expansion, with treatments potentially available in the UK by 2022. The process involves extracting, storing, and cloning hair follicles, but full regenerative treatments will take many years to develop.

community How soon is hair clone? Next five years?!

aiamab in Research/Science 15 upvotes 7 months ago

Hair cloning is humorously discussed as always being 5-7 years away, with skepticism about its near-term availability. Gene editing to reactivate dormant follicles is suggested as a more likely solution within the next ten years.

community HairClone received grant money to begin their work after crowdfunding failed

FollicleThought_com in Update 106 upvotes 5 years ago

HairClone received grant money to start work after crowdfunding failed. They aim to offer treatments in early 2021, pending UK FDA licensing.

community Dr. Tsuji and Riken to make important announcement on their hair cloning cure on Feb 10th.

roystreetcoffee in Update 56 upvotes 4 years ago

Dr. Tsuji and Riken announced a hair cloning cure with a 98.9% success rate, expected to be released in 10 years. Users expressed hope and skepticism about the affordability and timeline of the treatment.

community Why only the top of the head?!

dankaws in Chat 2 years ago

Why the top of the head is affected by hair loss more than other areas, and treatments such as surgery, medications like minoxidil, finasteride, and RU58841 to treat it.

community Why is nobody studying the difference between donor and balding hair?

Hairlssuf in Chat 89 upvotes 8 months ago

The conversation discusses why the difference between donor and balding hair isn't studied more to find a cure for hair loss. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community The MPB itch aka DHT itch is very real.

SendMeKittyPorn in Chat 9 upvotes 1 year ago

Hair loss itch is caused by DHT attacking follicles and stimulating nerves. Finasteride users who respond well don't experience this itch.

community Shiseido filed for this patent in May 2019. Let's get some big brain discussion on this.

pdawes 6 upvotes 5 years ago

The conversation discusses a patent filed by Shiseido for cloning Dermal Papilla (DP) cells to treat hair loss. The method involves using viral vectors to maintain the cells' growth-inducing properties, differing from Replicel's approach with Dermal Sheath Cup (DSC) cells.

community How does hair loss and recovery work?

Throwaway_1606 in Chat 12 upvotes 5 months ago

Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

community A New Therapeutic Channel to Come Soon: Hair Follicle Sugar Metabolism and Aldose Reductase

DSBarreto in Research/Science 133 upvotes 3 years ago

Hair loss therapies focusing on hair follicle sugar metabolism and aldose reductase. Potential treatments include magnesium supplements, avoiding high glycemic index foods, and antioxidants.

community September 2021 update from Dr. Kang-Yell Choi [Korean "cure"]

2mmSMP in Research/Science 31 upvotes 3 years ago

Dr. Kang-Yell Choi's company, CK Regeon, is developing a drug called KY19382 for hair regeneration, which involves creating fine wounds to activate stem cells. The drug is in the formulation development stage, targeting markets like the US and Korea.

community Boys how is no one seeing positive results from pyrilutamide

longjonsilver55 in Chat 28 upvotes 2 years ago

Pyrilutimide, a treatment for hair loss; it's effectiveness compared to other treatments such as Finasteride and RU58841; and some users’ experiences with the treatment.

community Vitamin C and hair growth PH levels

tironc1125 in Product 31 upvotes 3 years ago

The conversation is about using vitamin C and Magnesium L-Threonate for hair growth by reducing DHT binding to dermal papilla cells. The original post about vitamin C's pH levels and sebum control was possibly removed by a moderator.

community Hair loss causes are still a myth.

dannxFox in Chat 16 upvotes 3 years ago

The conversation discusses the complexity of hair loss causes, suggesting that DHT sensitivity alone doesn't fully explain it. Treatments mentioned include finasteride and dutasteride.

community What's your option on complementary treatment

Damned_lurker8 in Product 3 upvotes 8 months ago

The conversation discusses complementary treatments for hair loss while using finasteride and minoxidil, including scalp massagers, scrubs, coconut oil, and vitamin supplements. The user seeks opinions on these additional treatments.

community 3.5 months progress - oral dut 0.5mg and oral min 5mg - 26M

ZoneFuzzy2966 in Progress Pictures 143 upvotes 9 months ago

A user reports hair regrowth and thickening after 3.5 months using oral dutasteride (0.5mg) and oral minoxidil (5mg). They express gratitude for the information received from the community about hair loss treatments.