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GlossaryCancer Biology

study of how normal cells become cancerous and spread

Cancer Biology is the study of the cellular and molecular mechanisms that lead to the development and progression of cancer. It involves understanding how normal cells transform into cancerous cells, how they grow uncontrollably, and how they spread to other parts of the body. This field also explores genetic mutations, signaling pathways, and the tumor microenvironment, providing insights that are crucial for developing targeted therapies and improving cancer treatment.

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community Male pattern baldness, and mental health

in Finasteride/Dutasteride 330 upvotes 7 months ago

A 48-year-old man has been using minoxidil for 15 years and considered finasteride but stopped due to potential side effects. He is concerned about his mental health and the impact of hair loss on self-image, and he encourages support among men experiencing hair loss.

community Should I dedicate my university studies to solving hair loss?

in Research/Science 373 upvotes 1 year ago

A 20 year old male who is balding and considering switching to a biology/chemistry program in order to find a low-cost, accessible solution for hair loss. Replies discuss the merits of this idea as well as potential treatments such as Minoxidil, finasteride, RU58841, TM5614, and ADQ.

community HairClone aiming to 'Make Hairloss History' Launches Crowdfunding Campaign

29 upvotes 5 years ago

The post and conversation are about skepticism towards HairClone's crowdfunding campaign for a hair loss cure, with users expressing doubt and calling it a scam. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.

community September 2021 update from Dr. Kang-Yell Choi [Korean "cure"]

in Research/Science 32 upvotes 2 years ago

Dr. Kang-Yell Choi's company, CK Regeon, is developing a drug called KY19382 for hair regeneration, which involves creating fine wounds to activate stem cells. The drug is in the formulation development stage, targeting markets like the US and Korea.

community Prolactin’s role in antitumor activity of the immune system – a safety concern for HMI-115?

in Research/Science 3 upvotes 1 year ago

Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. Prolactin's role in immune system's antitumor activity raises safety concerns for HMI-115.

community This shit works like magic, aka 50 days on oral min&fin

in Progress Pictures 170 upvotes 1 month ago

A user shared their successful 50-day progress using oral minoxidil and finasteride for hair loss. They plan to switch to dutasteride after six months for potentially better results.

community I bought a microscope, how does my scalp/hairs look? I've been suffering diffuse thinning and hair loss after covid and never recovered (2 yrs ago) I eat healthy, in shape and workout.

in Progress Pictures 86 upvotes 5 months ago

A person with hair loss since COVID-19 is considering treatments like finasteride and minoxidil but is hesitant due to potential side effects. Suggestions include visiting a dermatologist, using a ketoconazole shampoo, and considering that post-COVID hair loss might be an autoimmune response.

community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

in Research/Science 92 upvotes 2 years ago

The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

community Could low blood flow to the head cause an increased rate of thinning?

in Chat 27 upvotes 2 years ago

The user started using finasteride, minoxidil, and biotin for male pattern baldness (MPB) and is experiencing rapid thinning. They are questioning if low blood flow to the head could be contributing to their hair loss.

community What’s your experience with using hinoki tree oil and/or procyanidin b2?

in Treatment 7 upvotes 3 years ago

Hair loss discussion includes treatments like hinoki tree oil and procyanidin b2. Experiences and effectiveness of these treatments are shared.

community Let's talk about natural options and last resorts.

in Chat 7 upvotes 4 months ago

The user discusses their long struggle with hair loss, considering various treatments like hair transplants, hair systems, and natural methods such as micro-needling, vitamin supplements, and a healthy lifestyle. They express concerns about side effects from drugs like finasteride and ultimately lean towards using a hair system for better appearance and confidence.

community Sunlight: Does it Stimulate Hair Growth or Hair Loss?

in Research/Science 61 upvotes 4 months ago

The conversation discusses whether sunlight exposure affects hair growth or loss, with mixed anecdotes and theories but no clear consensus. Some suggest moderate sunlight can benefit hair by providing vitamin D, while others doubt its effectiveness compared to treatments like Minoxidil or finasteride.

community Holy shit. Verteporfin may actually be the cure

in Research/Science 1013 upvotes 9 months ago

The post and conversation discuss Verteporfin's potential as a hair loss treatment. It's shown promise in regrowing hair after transplants and might be effective with microneedling.

community 5 month results on natural protocol, i made a post after 3 mont of treatment wich you can find in my profile. I used different massages(detumescence therapy, wooden brush, tom hagerty exercises)vitamins(d3,fish oil, biotin,msm, magnesium) drank green tea and ate pumpkin seeds( reduces dht)

in Is this regrowth? 148 upvotes 1 year ago

The user "Zealousideal-Pack340" shared their 5-month results on a natural hair loss treatment protocol, which included massages, vitamins, green tea, and pumpkin seeds. Some users suggested using medications like finasteride and minoxidil for better results, while others criticized the effectiveness of natural remedies. Overall, there was no clear consensus on the progress of the user's hair regrowth.

community Mark Normand talks about finasteride experience

in Finasteride/Dutasteride 825 upvotes 1 year ago

The conversation is about hair loss and the use of finasteride as a treatment. Some users share their positive experiences with finasteride, while others mention side effects they have experienced.

community How do we only have two treatments to combat hair loss at this point in time?

in Chat 212 upvotes 1 year ago

The post discusses frustration over the limited and not always effective treatments for hair loss, mainly Minoxidil and Finasteride. The conversation includes mentions of potential new treatments like GT20029, HMI-115, CosmeRNA, KX-826, and microneedling, but also highlights the challenges of funding and prioritizing research in this area.

community Dr Huberman – Cafeine when rubbed on the scalp can be as effective at times as minoxidil because it triggers 1GF-1

in Update 266 upvotes 1 year ago

Whether topical caffeine can be as effective for hair growth as minoxidil and finasteride, with various replies discussing the efficacy of these treatments and criticism of Dr. Huberman's research methods.

community Kintor Pharma Announces Positive Top-line U.S. Phase I Trial Results of GT20029, the World’s First Topical Use PROTAC Compound

in Research/Science 127 upvotes 1 year ago

The conversation discusses positive initial trial results for GT20029, a topical compound for hair loss that degrades androgen receptors, potentially requiring only weekly application. Participants express hope for this treatment to be more effective and convenient than current options like Minoxidil, Finasteride, and RU58841.

community find a cure for this shit already

in Chat 205 upvotes 3 years ago

Treatments used to prevent and treat male pattern baldness, the difficulty in finding a permanent cure for hair loss, and the potential financial motivations of companies not wanting to find a cure.

community So it turns out Post Finasteride Syndrome was never real?

in Finasteride/Dutasteride 265 upvotes 1 month ago

Post Finasteride Syndrome (PFS) is debated, with some users reporting severe side effects from finasteride, while others believe these effects are rare or psychosomatic. Treatments discussed include finasteride, minoxidil, and RU58841.

community RU-58841 Lung Disease Possibility | Chest pain, "heart issues", etc

in Treatment 23 upvotes 6 months ago

Some users of RU-58841 report cardiovascular symptoms like heart palpitations and chest tightness, which may be linked to its metabolites causing lung disease. The safety of RU-58841 is uncertain due to lack of long-term data and concerns about product purity, especially from gray market sources.

community Ultimate Hairloss Flowchart (for beginners)

in Treatment 247 upvotes 9 months ago

The conversation discusses a hair loss flowchart for beginners, with mixed opinions on its effectiveness. Treatments mentioned include minoxidil, finasteride, dutasteride, microneedling, and vitamins.

community C’est terrible - at my wits end

in Female 445 upvotes 9 months ago

A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

community Huberman tweet about finasteride

in Finasteride/Dutasteride 275 upvotes 9 months ago

The conversation is about the side effects of finasteride, including Post Finasteride Syndrome, with varied personal experiences and differing views on the credibility of information sources. Some participants also discuss using minoxidil as a hair loss treatment.

community Are there ever going to be any oral DHT blocking treatments in the future?

in Product 6 upvotes 10 months ago

The discussion revolves around the need for future oral DHT blockers for hair loss treatment that don't have the side effects of current options like Finasteride and Dutasteride. One user suggests that the future of hair loss treatment will likely be topical anti-androgens, as they can target hair follicles without affecting the entire system.

community New Treatments, and a Huge Group Buy with Lots of Research

in Research/Science 111 upvotes 11 months ago

A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

community Are the japanese Finasteride 10 year studies even relevant to caucasian men - especially young ones?

in Technology 108 upvotes 11 months ago

The conversation is about the effectiveness of hair loss treatments, specifically finasteride and dutasteride, in different populations. Some users believe that the results of Japanese studies may not be relevant to Caucasian men, especially young ones, and that East Asians may respond better to these treatments. Others argue that clinical studies should be the basis for decision-making, while acknowledging that individual responses to medications can vary.

community How is it that golden era bodybuilders kept their hair while blasting gear while in the modern era most are bald? I’m convinced there’s something in our food and water causing MPB to speed up

in Satire 729 upvotes 1 year ago

The conversation is about the difference in hair loss between bodybuilders in the "Golden Era" and modern bodybuilders. Some users speculate that factors such as the types and doses of steroids used, genetics, diet, microplastics, and overall health may contribute to hair loss. Hair loss prevention medication and transplants are mentioned as potential treatments.

community Testosterone and hair loss seeming irrelevance

in Research/Science 83 upvotes 1 year ago

The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.

community Why is dht bad for scalp hair but good for hair on the rest of body?

in Satire 109 upvotes 1 year ago

The conversation discusses why DHT (dihydrotestosterone) negatively affects scalp hair but promotes growth elsewhere on the body. Various opinions include genetic predispositions, differences in hair follicle reactions to DHT, and the potential role of Omega-3 in reducing inflammation and promoting hair health.