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GlossaryRapamycin

drug that inhibits mTOR to suppress immune response

Rapamycin, also known as Sirolimus, is a drug originally discovered in soil bacteria from Easter Island. It is primarily used as an immunosuppressant to prevent organ transplant rejection and has shown potential in extending lifespan and treating certain diseases by inhibiting a protein called mTOR, which regulates cell growth and metabolism.

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community Rapamycin for Longevity 2022 - Hair pigmentation and regeneration in mice

in Chat 6 upvotes 2 years ago

The conversation is about the potential benefits of Rapamycin for hair pigmentation and regeneration, based on effects observed in mice. The original poster is seeking personal experiences from others using Rapamycin for longevity.

community Research suggests that drugs rapamycin and metformin have hair regeneration properties

3 upvotes 6 years ago

Rapamycin and metformin may have hair regeneration properties. Specific treatments discussed include Minoxidil, finasteride, and RU58841.

community Topical rapamycin, metformin, a-kg grow hair

in Research/Science 13 upvotes 4 years ago

The conversation discusses the potential of topical rapamycin, metformin, and alpha-ketoglutarate (a-KG) for hair growth, with skepticism expressed about their effectiveness based on personal experience and existing use. It also mentions AICAR, known as cardarine or GW, which is not suitable for long-term use due to cancer risks in animal studies and its similarity to metformin.

community The Efficacy of Topical Rapamycin for Hair Regrowth

in Treatment 6 upvotes 1 year ago

The conversation discusses the effectiveness of topical Rapamycin for hair regrowth and color restoration. Specific treatments mentioned are Minoxidil, Finasteride, and RU58841.

community Self-Experiment - Topical Rapamycin or a-KB

in Treatment 4 upvotes 2 years ago

A user plans to create a DIY topical treatment for hair loss using Rapamycin, possibly combined with alpha-ketoglutaric acid (a-KG). They discuss the concentration and formulation process for Rapamycin, considering safety and skin penetration, and intend to apply it every other day to the scalp.

community Hair Regrowth by Transdermal Dissolvable Microneedles Loaded with Rapamycin and Epigallocatechin Gallate Nanoparticles - PubMed

in Research/Science 15 upvotes 2 years ago

The conversation discusses hair regrowth using dissolvable microneedles loaded with rapamycin and epigallocatechin gallate nanoparticles. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.

community Anyone else tried BeauTop aka "Primal Hair"? I assumed their studies were faked/exaggerated but have had surprising results

in Research/Science 1 upvotes 2 years ago

A user tried BeauTop (Primal Hair) for hair loss, alongside a topical blend of finasteride, rapamycin, and caffeine, and noticed positive results. They cannot confirm BeauTop is the sole reason for improvement and are curious about others' experiences.

community TresslessGPT is now available for free

in General 386 upvotes 5 months ago

Tressless GPT is now free and accessible for hair loss advice. Treatments discussed include Minoxidil, finasteride, RU58841, dutasteride mesotherapy, topical melatonin, microneedling, and rapamycin.

community TresslessGPT is available to ChatGPT Plus users

in 📣 Announcement 107 upvotes 10 months ago

The conversation introduces a specialized chatbot for ChatGPT Plus users that provides advice on hair loss treatments, drawing from research and community insights. It mentions treatments like RU58841, the "big 4" (likely minoxidil, finasteride, ketoconazole, and tretinoin), dutasteride mesotherapy, topical melatonin, microneedling, and rapamycin.

community Is the a way to get dutasteride in france without prescription

in Finasteride/Dutasteride 9 upvotes 1 year ago

Hair loss treatments discussed include Minoxidil, Finasteride, and RU58841. A user suggests using EUdoctor app to get a prescription for Dutasteride and shares the cost breakdown.

community RT1640 - Gray Hair Reversal Recipe

in Research/Science 3 upvotes 2 years ago

The conversation discusses a hair loss treatment formulation containing cyclosporin, minoxidil, and tacrolimus, and mentions ongoing research on hair color reversal. The treatment showed high efficacy in restoring hair color in trials with 40 to 50 people.

community I made a Dashboard to track where to buy Finasteride/Minoxidil in Europe/US/… without prescription

in Technology 1 year ago

Finding and comparing providers of hair loss treatments such as Finasteride, Minoxidil and potentially Dutasteride, RU58841 and other research chemicals; the user has created a website to track suppliers of these products around the world; and various online pharmacies are recommended, including those that ship to certain countries.

community New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase

in Research/Science 122 upvotes 6 months ago

Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Is there any new drug that looks promising ?

in Research/Science 25 upvotes 8 months ago

The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.

community 0.5mg Dutasteride promotes more “regrowth” than 5mg oral Minoxidil

in Research/Science 117 upvotes 9 months ago

Dutasteride promotes more hair regrowth than Minoxidil. Users discuss combining treatments for better results and share personal experiences with side effects.

community 1 year on fin. No results. I give up.

in Finasteride/Dutasteride 43 upvotes 2 years ago

A user who has been taking finasteride, minoxidil, and microneedling for one year with no results, and the replies discuss other treatments, including dutasteride, which is feared due to potential side effects.

community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

in Research/Science 736 upvotes 2 years ago

A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.