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This study found that fluorescence excitation spectroscopy could be a promising noninvasive tool for assessing the effects of comedolytic agents like retinoids on acne-like lesions in rhino mice.

This study found that treating the skin of Mexican hairless dogs with different tretinoin formulations reduced comedones and lightened skin color, suggesting its potential as a model for evaluating retinoid activity.

In this study, both 2.5% benzoyl peroxide gel and 0.1% adapalene gel exhibited comedolytic effects on the spontaneous comedogenic rhino mouse model.

Birth control pills help treat acne, especially when caused by excess male hormones, and are safe to use with antibiotics.

This study found that 2MbisP increases epidermal thickening more rapidly than atRA in rhino mice, while both compounds similarly reduce utricle size.