This study found that transgenic expression of Endothelin 3 in mice can maintain a dark pigmentation phenotype independently of Mc1r signaling by regulating melanogenic genes.
January 2014 in “University of the Arts London Research Online (University of the Arts London)” Certain ingredients can help protect hair color.
6 citations
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September 2013 in “Advanced materials research” This study found that non-ionic silicone emulsion best protected hair color from UV-induced fading, outperforming honeysuckle extract and benzophenone-3, with significant effects in both dyed and virgin hair.
November 2025 in “International Journal of Biological Macromolecules” This study introduced an eco-friendly enzymatic hair dyeing process utilizing laccase-catalyzed polymerization of hematoxylin, achieving intense, long-lasting color comparable to commercial dyes while enhancing hair strength and offering antioxidant and UV-shielding benefits.
12 citations
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October 2007 in “PubMed” This study reports that keratin actives may protect various hair types from chemical damage, restore damaged fibers' mechanical strength, and reduce color fading.