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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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research Co-Localization of Alopecia Areata and Lichen Planopilaris in a Patient Receiving Immunosuppressants: A Rare Case
A woman on immunosuppressants developed two rare scalp conditions, which improved with specific treatments.
research Existence of trichohyalin-keratohyalin hybrid granules: Co-localization of two major intermediate filament-associated proteins in non-follicular epithelia
Trichohyalin is found in non-hair tissues and works with filaggrin in certain skin areas and conditions.
research Toluene Diisocyanate Disposition and Co-Localization of Immune Cells in Hair Follicles
The study investigated the immune sensitization caused by skin exposure to toluene diisocyanate (TDI) using a murine model. BALB/c mice were exposed to TDI, and analyses revealed that TDI-haptenated proteins (TDI-hp) localized in the stratum corneum, hair follicles, and sebaceous glands. These proteins co-localized with immune cells such as CD11b(+), CD207(+), and CD103(+) in hair follicles and sebaceous glands, indicating these areas as reservoirs for TDI-hp. The study identified cytoskeletal and cuticular keratins and mouse serum albumin as major haptenated species, suggesting a mechanism for immune recognition and potential sensitization following TDI exposure.
research Severe Lichen Planus With Co-Localization of Vitiligo: A Rare and Unusual Case
A 13-year-old boy had both lichen planus and vitiligo, suggesting a possible link between the two conditions.
research Localization of Cathepsins B, D, L, LAMP-1 and .MU.-Calpain in Developing Hair Follicles.
Lysosomal proteases and cytoplasmic enzymes help hair follicle cells develop and differentiate.
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5 / 487 resultscommunity Funding for sending RU58841 from rudirect.co.uk to Janoshik Analytical
The conversation is about a user trying to fund lab testing for RU58841 to verify its legitimacy, as there are doubts about its effectiveness. Some users express skepticism about RU58841, suggesting alternatives like KX-826.
community New company Amplifica gets $11.8 million in financing for development of its hair loss products. Dr. Maksim Plikus and William Rassman are co-founders.
New company Amplifica receives $11.8 million for hair loss product development, co-founded by Dr. Maksim Plikus and William Rassman. Users discuss undisclosed product candidates and application methods.
community Best Sources for High Purity Ru58841
The conversation is about finding high-purity RU58841 solutions for hair loss treatment, with mentions of Anagenic, Selleckchem, MV Supplement, and rudirect.co.uk as potential sources. Users discuss their experiences and preferences regarding product quality and shipping.
community Is this any good to apply minoxidil with?
The conversation discusses using a dropper to apply Minoxidil for hair loss treatment. The user seeks advice on the appropriate number of drops to use.
community Woolly mice but no hair growth treatment for humans yet 🤷♂️
Hair regrowth treatments are effective in mice but not yet available for humans. The discussion humorously highlights frustration over this disparity and mentions a project to genetically modify elephants to resemble mammoths.