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mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials
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highly targeted anti-androgen that might have minimal systemic effects
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5 / 1000+ resultsresearch Clinical Study of Patients with Female Pattern Hair Loss Over a 10-Year Period
Treating underlying metabolic and hormonal issues is key to managing female hair loss.
research Safety Profile and Efficacy of Biosea Revive Serum for Hair Growth Through In Vitro Assessment and Clinical Evaluation
Biosea® Revive Serum is safe and effective for improving hair growth and health.
research Autologous Micrografts from Scalp Tissue: Trichoscopic and Long-Term Clinical Evaluation in Male and Female Androgenetic Alopecia
Micrografts improve hair density and thickness without side effects.
research Clinical Efficacy of a Topical Compounded Formulation in Male Androgenetic Alopecia: Minoxidil 10%, Finasteride 0.1%, Biotin 0.2%, and Caffeine Citrate 0.05% Hydroalcoholic Solution
The topical solution improved hair density and appearance in men with androgenetic alopecia.
research Historical and Current Adenosine Receptor Agonists in Preclinical and Clinical Development
The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.
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5 / 1000+ resultscommunity Brief summary of new dutasteride study linked to infertility and the limitations/problems with the study
Dutasteride treatment may decrease sperm concentration, but levels remain above WHO recommendations and recover after discontinuation. The study has limitations, including small sample size and lack of pre-treatment sperm data, and does not assess other fertility factors.
community GT20029 China Phase II Trial For AGA Reached Primary Endpoint
The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.
community Summary of Procapil video by Haircafe
Procapil is marketed as a natural hair loss treatment but lacks strong evidence and is industry-biased. Minoxidil and Finasteride are the only FDA-approved treatments for androgenetic alopecia.
community Why is Finasteride seen as “scary” for men, but hormonal birth control is totally normalized for women?
Finasteride is seen as risky for men due to side effects like erectile dysfunction, while hormonal birth control for women is normalized despite its side effects. The discussion points out a double standard influenced by societal and gender norms.
community microneedle, any long term users damage?
Microneedling is effective for hair growth, especially when combined with finasteride and minoxidil, but concerns exist about potential long-term skin damage. Users report increased collagen and elastin deposition, but the long-term effects on the scalp remain uncertain.