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    GlossaryClinical Findings

    observations and results from a patient's medical examination

    Clinical findings refer to the observations and results gathered by healthcare professionals during a patient's examination. These can include physical signs, symptoms reported by the patient, laboratory test results, and imaging studies. For example, in the context of alopecia, clinical findings might include visible hair loss patterns, scalp condition, and results from blood tests to check for underlying conditions.

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      learn GT20029

      research compound made to degrade androgen receptors in scalp

      learn Rapamycin

      mTOR regulator and immunosuppressant used more recently for anti-aging and hair regrowth

      learn Verteporfin

      chemical that might completely regrow follicles from hair transplant extractions

      learn Pyrilutamide

      highly targeted anti-androgen that might have minimal systemic effects

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      community FINASTRIDE and switch to DUTASTRIDE, my experience

      in Progress Pictures  134 upvotes 2 months ago
      The user shared their experience with Finasteride and Dutasteride for hair loss. They initially had success with Finasteride but switched to Dutasteride after experiencing shedding, which continued, and are now considering a hair transplant.

      community Why don’t people just just DUT instead of FIN?

      in Finasteride/Dutasteride  48 upvotes 8 months ago
      The conversation discusses the use of dutasteride (DUT) versus finasteride (FIN) for hair loss treatment, with some users preferring DUT for its effectiveness while others choose FIN due to its approval status, better long-term data, and lower risk of side effects. Users share personal experiences with both medications, including side effects and effectiveness.

      community Any New Findings or Interesting Research?

      in Research/Science  24 upvotes 9 months ago
      The conversation is about seeking new research on hair loss treatments beyond the commonly known ones like Minoxidil and Finasteride. Additions to the list of treatments include topical caffeine, alfatradiol, fluridil, stemoxydine, and upcoming treatments like TDM-105795 and verteporfin.

      community Verteporfin and Microneedling

      in Treatments 5 months ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.