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Did you mean Chronic Graft-Versus-Host Disease?

Glossary Chronic Graft-Versus-Host Disease

condition where transplanted cells attack recipient's body long-term

Chronic Graft-Versus-Host Disease (cGVHD) is a condition that can occur after a stem cell or bone marrow transplant, where the donated cells (the graft) attack the recipient's body (the host). This immune response can lead to long-term complications affecting various organs, including the skin, liver, and gastrointestinal tract, and can manifest as rashes, liver dysfunction, and digestive issues.

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Risk Factors and Characterization of Vitiligo and Alopecia Areata in Patients With Chronic Graft-Versus-Host Disease

research Risk Factors and Characterization of Vitiligo and Alopecia Areata in Patients With Chronic Graft-vs-Host Disease

27 citations , September 2014 in “JAMA dermatology”

In this NIH study, female donor to male recipient sex mismatch was significantly associated with the development of vitiligo and/or alopecia areata in patients with chronic graft-vs-host disease.

High Frequency of Cutaneous Manifestations Including Vitiligo and Alopecia Areata in a Prospective Cohort of Patients with Chronic Graft-Versus-Host Disease

research High frequency of cutaneous manifestations including vitiligo and alopecia areata in a prospective cohort of patients with chronic graft-vs-host disease

17 citations , June 2016 in “Croatian Medical Journal”

In this study, vitiligo and alopecia areata were more common among patients with chronic graft-vs-host disease than previously reported, linked to higher NIH skin scores and greater immunosuppressive treatment.

research Alopecia Universalis and Chronic Graft-vs-Host Disease Treated With Ruxolitinib

4 citations , October 2018 in “JAMA Dermatology”

Ruxolitinib may help treat hair loss and symptoms in patients with chronic graft-versus-host disease.

research Chronic graft versus host disease and skin

32 citations , August 2003 in “Journal of the European Academy of Dermatology and Venereology”

This article reviews the clinical aspects and potential mechanisms of chronic graft vs host disease skin manifestations, describing a novel form of premature skin aging, but presents no new research findings.

Rapid Full Engraftment and Successful Immune Reconstitution After Allogeneic Hematopoietic Stem Cell Transplantation With Reduced Intensity Conditioning in Omenn Syndrome

research Rapid full engraftment and successful immune reconstitution after allogeneic hematopoietic stem cell transplantation with reduced intensity conditioning in Omenn syndrome

8 citations , August 2009 in “Pediatric transplantation”

This report presents a case where a patient with Omenn syndrome, complicated by cytomegalovirus infection, was successfully treated using reduced intensity conditioning allogeneic HSCT from a sibling donor.

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community Wtf have we been doing for the last 30 years

in Treatment 548 upvotes 1 year ago

Hair loss treatments like finasteride, minoxidil, and dutasteride work but have side effects. A permanent cure is still not available due to the complexity of hair loss and limited investment.

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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