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GlossaryDeoxycholic Acid

bile acid aiding fat digestion and absorption

Deoxycholic Acid, also known as DCA, is a bile acid that is naturally produced by the liver and stored in the gallbladder. It helps in the digestion and absorption of fats in the small intestine. In medical and cosmetic applications, deoxycholic acid is used in treatments to break down and absorb fat cells, such as in the injectable treatment Kybella for reducing submental fat (double chin).

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research The Implication of Mechanistic Approaches and the Role of the Microbiome in Polycystic Ovary Syndrome: A Review

1 citations , January 2023 in “Metabolites”

Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.

research Serum Metabolomics Study of Polycystic Ovary Syndrome Based on Liquid Chromatography–Mass Spectrometry

71 citations , January 2014 in “Journal of Proteome Research”

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

research Obstetric Dermatology

January 2009 in “Springer eBooks”

The document concludes that managing skin conditions during pregnancy is important and requires specialized care.

research Metabolomics Reveals Metabolites Associated with Hair Follicle Cycle in Cashmere Goats

May 2024 in “BMC veterinary research”

Metabolites and diet affect hair growth cycles in cashmere goats.

research Very-Long-Chain Acyl-CoA Synthetases

191 citations , November 2007 in “Journal of Biological Chemistry”

Very-long-chain acyl-CoA synthetases and fatty acid transport proteins play key roles in fatty acid metabolism and lipid processing in different tissues.

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community Bile Acid-Mediated DHT Dysregulation Hypothesis

in Research/Science 13 upvotes 1 year ago

Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.