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    GlossaryCentral Centrifugal Cicatricial Alopecia (Central Scarring Alopecia)

    scarring hair loss starting at the scalp's crown, common in African American women

    Central Centrifugal Cicatricial Alopecia (CCCA) is a type of scarring hair loss that typically starts at the crown of the scalp and spreads outward in a circular pattern. It is most commonly seen in African American women and can lead to permanent hair loss due to the destruction of hair follicles and subsequent scarring.

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      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 2 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.