7 citations
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February 2022 in “Stem cell reviews and reports” Skin cells show flexibility in healing wounds and forming tumors, with potential for treating hair disorders and chronic ulcers.
Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.
1160 citations
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November 2018 in “Physiological Reviews” The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
211 citations
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May 2018 in “Trends in cell biology” Different types of skin cells play specific roles in development, healing, and cancer.
2 citations
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July 2025 in “Frontiers in Veterinary Science” This review discusses the critical role of microRNAs (miRNAs) in regulating hair follicle development and cycling in cashmere goats, which are prized for their fine fiber. It highlights the influence of key miRNAs, such as miR-31, miR-22, and miR-214, on hair follicle morphogenesis, regeneration, and fiber traits. Recent advances in single-cell RNA sequencing and spatial transcriptomics have provided new insights into cellular heterogeneity and lineage specification. Integrative multi-omics approaches reveal complex regulatory networks involving miRNAs, while AI-driven analytics enhance biomarker discovery and therapeutic target identification. These findings inform breeding strategies to improve cashmere fiber quality and offer minimally invasive diagnostic tools for hair disorders. Future directions include improved miRNA delivery methods and AI-powered multi-omics approaches to advance hair follicle biology understanding and practical applications in medicine and agriculture.