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research PLA2R1 Overexpression Causes Podocyte Injury by Inhibiting the Cell Cycle: A Clinical Cross-Sectional Investigation and Cellular Study

June 2025 in “International Journal of Nephrology and Renovascular Disease”

This study suggests that PLA2R1 overexpression in PMN affects the podocyte cycle and may involve an additional immune response, which could provide new directions for PMN treatment development.

research Faculty Opinions recommendation of Conditional telomerase induction causes proliferation of hair follicle stem cells.

October 2005 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

This study found that induced TERT expression in mouse skin epithelium rapidly transitions hair growth from the resting to active phase by promoting stem cell proliferation through a non-telomere related mechanism.

research ILDS Newsletter No. 29

January 2013 in “Dermatology”

The ILDS Newsletter reported on efforts to support albinism patients in Tanzania and dermatological conferences.

research The Effect of Ruby Laser Light on Cellular Proliferation of Epidermal Cells

9 citations , November 1999 in “Annals of Plastic Surgery”

This study found that ruby laser hair removal causes microscopic epidermal damage but does not lead to cellular hyperproliferation, unlike ultraviolet-irradiated cell damage.

research The causes of age-related alopecia from the point of view of modern morphology

January 2025 in “JOURNAL of SIBERIAN MEDICAL SCIENCES”

This review highlights morphological factors contributing to age-related alopecia and suggests further research to understand and potentially mitigate cellular aging processes affecting hair quality.

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Community Join

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community The Real Cause Of Androgenetic Alopecia

675 upvotes 1 year ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community Is DHT actually the cause of male pattern hair loss or just a correlating factor? Why I think the research is more complicated than we're told and why I've been looking into GHK-Cu

78 upvotes 4 months ago

DHT is not the only cause of male pattern hair loss; genetic sensitivity, inflammation, and fibrosis also contribute. GHK-Cu, a copper peptide, is being explored as an alternative treatment to finasteride and minoxidil, showing potential in improving follicle health.

community Dental technician is convinced that he has found the cause of pattern hair loss

314 upvotes 2 years ago

A dental technician claims malocclusion causes pattern hair loss due to poor scalp circulation. Users debate this, noting treatments like finasteride, minoxidil, and microneedling focus on DHT and blood flow.

community Cell senescence-targeted treatment for hair loss, has anyone tried any products/enzymes etc. that use this theory

5 upvotes 1 year ago

DHT causes hair loss by driving cells into senescence, and a polyphenol in black chokeberry may reverse this. A product using this theory is being considered for use alongside finasteride, minoxidil, and microneedling.

community My Theory Of Androgenic Alopecia

16 upvotes 10 months ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

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Learn

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learn Folic acid

How does folic acid support hair follicle health and growth at a cellular level? Folate is required for the DNA synthesis that fast-dividing hair matrix cells depend on, and severe deficiency causes anemia—but no published trial has given folic acid to people with hair loss and measured the result, so a growth effect is a mechanism, not a finding.

learn Adenosine

Molecule the body uses for energy, used as a cosmetic hair-lotion ingredient

learn Tretinoin

Vitamin A retinoid cream, prescribed for acne

learn Melatonin

Hormone that regulates sleep, sold as a supplement

learn vitamin b2

What does vitamin B2 do for cellular energy, and does it affect scalp circulation? Riboflavin (vitamin B2) is needed for cell energy metabolism, according to the NIH. No study has shown that it improves scalp circulation or hair growth in people who are not deficient.

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