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research Injury modifies the fate of hair follicle dermal stem cell progeny in a hair cycle‐dependent manner

16 citations , March 2019 in “Experimental dermatology”

This study found that injury affects the behavior of hair follicle dermal stem cells, steering them towards recruitment into the dermal papilla, a shift influenced by the hair cycle stage.

Chemotherapy-Induced Alopecia: Emotional Distress and Mitigation Strategies

research Chemotherapy-Induced Alopecia

155 citations , March 2009 in “Seminars in Cutaneous Medicine and Surgery”

This review covers various strategies to manage chemotherapy-induced alopecia, highlighting that agents like AS101 and minoxidil can reduce its severity but not prevent it, with no new clinical results reported.

research Increased Rate of Hair Regrowth in Mice with Constitutive Overexpression of Del1

6 citations , August 2007 in “Journal of Surgical Research”

In this study, constitutive expression of Del1 in mice did not affect wound healing but was associated with increased hair growth following anagen induction.

research 12-Chloracetyl-PPD, a novel dammarane derivative, shows anti-cancer activity via delay the progression of cell cycle G2/M phase and reactive oxygen species-mediate cell apoptosis

18 citations , December 2016 in “European journal of pharmacology”

In this study, 12-Chloracetyl-PPD showed anti-cancer activity by inhibiting cancer cell viability and inducing apoptosis through reactive oxygen species production without harming normal cells.

research Reply to: The ends of a conundrum?

March 2007 in “Journal of Cell Science”

This study found that keratin K1014chim expression in mice did not reduce epidermal cell proliferation but increased susceptibility to benign tumors, challenging previous beliefs about K10's role in inhibiting tumor development.

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Community Join

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community PP405 Won't Work Long Term: Hair Follicle Damage Due to Abuse of the ISR System

67 upvotes 11 months ago

PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.

community My Theory Of Androgenic Alopecia

16 upvotes 10 months ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

community Haircafe on why microneedling is bad for hair growth

in Microneedling 157 upvotes 2 years ago

Microneedling combined with minoxidil and finasteride shows significant hair regrowth, though opinions on its effectiveness vary. Some users report substantial benefits, while others highlight the need for more research and consistency in application.

community True hair loss Vs shedding cycle

2 upvotes 7 months ago

The user stabilized hair loss with oral finasteride, dutasteride, and topical minoxidil, and underwent a stem cell and PRP procedure. Recent increased hair shedding may be due to restarting dermarolling, affecting minoxidil absorption, or the waning effects of the stem cell treatment.

community Anyone heard of HairStemCell Transplant? They claim not needing to pull the entire hair cell, allowing reuse of same donor area.

4 upvotes 8 years ago

HairStemCell Transplant claims to reuse the donor area without removing the entire hair cell, but results in finer hair that may not regrow after cycles. The technique is costly and less effective than traditional transplants for full coverage.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Stem Cell Factor

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Clinics

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