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      learn Follistatin

      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

      learn Exosomes

      Microscopic delivery system that sends growth-promoting signals to hair follicles

      learn Microneedling

      technique to create small wounds in skin to activate collagen production and hair growth

      learn Stemoxydine

      chemical from L'Oreal that encourages hair to enter growth phase

      learn PP405

      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

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      community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

      in Research/Science  92 upvotes 2 years ago
      The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

      community Expectations control for SCUBE3

      in Research/Science  22 upvotes 8 months ago
      SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.