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This study found that mint leaf and Aloe vera serum together significantly reduced CDK1 expression, which may help prevent chemotherapy-induced alopecia in rats, although only mint serum alone reduced CDC25 expression.

The study found that safflower extract may help protect human follicle dermal papilla cells from cisplatin-induced damage, suggesting its potential as an adjuvant in chemotherapy to mitigate hair follicle cell damage.

This study found that deleting specific super-enhancer regions in mice affects CD25 expression in a cell type-specific manner, leading to autoimmune alopecia in some cases and revealing distinct regulatory mechanisms for constitutive and inducible expression of CD25.

This study identified elevated CD25 on secreting CD4 regulatory T cells as a genetic risk factor for androgenetic alopecia, with certain plasma proteins acting as mediators in this causal relationship.

This study found that specific immune cell phenotypes, particularly CD25 on CD4 Treg cells, were causally linked to androgenic alopecia, suggesting potential targets for immune-based therapies.