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GlossaryCD4 (CD4+ lymphocyte)

protein on immune cells crucial for signaling and HIV entry

CD4 is a type of protein found on the surface of certain immune cells, such as T-helper cells. These cells play a crucial role in the immune system by signaling other cells to perform their functions. CD4 is also the primary receptor that HIV uses to enter and infect these immune cells, which can lead to a weakened immune system.

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research Mucocutaneous Manifestations in HIV-Infected Patients and Their Relationship to CD4 Lymphocyte Counts

7 citations, August 2020 in “Scientifica”

Most HIV-positive patients had skin problems, and conditions like oral thrush and boils were linked to weaker immune systems.

research Spectrum of Mucocutaneous Manifestations in HIV-Infected Patients and Its Correlation with CD4 Lymphocyte Count

12 citations, July 2014 in “International Journal of STD & AIDS”

HIV patients with lower CD4 T cell counts often have more skin problems.

Topical Mechlorethamine Restores Autoimmune-Arrested Follicular Activity in Mice with an Alopecia Areata-Like Disease by Targeting Infiltrated Lymphocytes

research Topical Mechlorethamine Restores Autoimmune-Arrested Follicular Activity in Mice with an Alopecia Areata-Like Disease by Targeting Infiltrated Lymphocytes

19 citations, March 2003 in “Journal of Investigative Dermatology”

Mechlorethamine treatment regrew hair in mice by killing immune cells causing hair loss without harming hair follicles.

Alopecia in Association with Severe Seborrhoeic Dermatitis Following Combination Antiretroviral Therapy for Acute Retroviral Syndrome

research Alopecia in Association with Severe Seborrhoeic Dermatitis Following Combination Antiretroviral Therapy for Acute Retroviral Syndrome

12 citations, June 2005 in “Journal of the European Academy of Dermatology and Venereology”

A man with HIV developed skin and hair issues after starting HIV treatment, which improved with topical treatment.

research Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells

47 citations, March 2019 in “Journal of immunology research”

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

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