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The optimal concentration for caffeine release in gel form is 0.2% caffeine and 2.3% chitosan.
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September 2021 in “International Journal of Molecular Sciences” Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.
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December 2021 in “Pharmaceutics” Phospholipid soft vesicles improve topical drug delivery for better skin condition treatments.