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Glossary Cancer

uncontrolled growth and spread of abnormal cells

Cancer, also known as a malignant tumor or malignant neoplasm, is a group of diseases characterized by the uncontrolled growth and spread of abnormal cells. If the spread is not controlled, it can result in death. Cancer can develop in almost any part of the body and often forms a mass called a tumor, although not all cancers form tumors (e.g., leukemia). The study and treatment of cancer fall under the field of oncology.

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Research

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Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors

research Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors

402 citations , August 2011 in “Cancer research”

This study found that castration-resistant prostate cancers resistant to CYP17A1 inhibitors may still depend on steroids and could respond to therapies targeting de novo intratumoral steroid synthesis.

research Efficacy and safety of a novel anti‐HER2 therapeutic antibody RC48 in patients with HER2‐overexpressing, locally advanced or metastatic gastric or gastroesophageal junction cancer: a single‐arm phase II study

147 citations , October 2021 in “Cancer Communications”

This study found that the novel anti-HER2 antibody RC48 demonstrated promising activity and manageable safety in patients with HER2-overexpressing, advanced gastric or gastroesophageal junction cancer after at least two prior chemotherapy lines.

research Increased copy number of the TERT and TERC telomerase subunit genes in cancer cells

145 citations , May 2008 in “Cancer Science”

This review discusses how increased gene copy number for telomerase components may contribute to telomerase up-regulation in cancer cells, although the exact mechanisms are not fully understood.

research Normal stem cells and cancer stem cells: similar and different

126 citations , April 2010 in “Seminars in Cancer Biology”

This review discusses the similarities and differences between normal stem cell proliferation and cancer cell oncogenesis and concludes that understanding these mechanisms could improve cancer treatment strategies, but it reports no novel findings.

research Stretching the limits: from homeostasis to stem cell plasticity in wound healing and cancer

124 citations , February 2018 in “Nature Reviews Genetics”

This review covers recent findings on stem cell plasticity under normal and cancerous conditions but presents no new experimental results, highlighting implications for regenerative medicine and cancer treatments.

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Learn

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learn Hair Transplant

Can a hair transplant cause cancer? Hair transplants do not cause cancer according to most providers.

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community They’re curing cancer before solving baldness

285 upvotes 1 month ago

The conversation humorously discusses the prioritization of curing cancer over solving baldness, with mentions of treatments like finasteride and dutasteride. Participants express frustration over the lack of focus on hair loss solutions compared to cancer research.

community Does RU58841 potentially cause cancer?

in Research/Science 1 year ago

RU58841 may pose cancer risks due to its antiandrogen properties and lack of long-term safety data. Using it is considered a high-risk experiment with unknown potential for harm.

community Does drinking topical minoxidil increase cancer risk?

in Minoxidil 1 year ago

A user has been using sublingual minoxidil for hair loss due to difficulty obtaining pills and is concerned about cancer risk from ethanol exposure. Other users advise against this method, suggesting topical application instead, and debate the potential risks of ingesting topical minoxidil.

community Evolution theory: AGA is your body trying to reduce the risk of prostate cancer by exposing your scalp to more UV

in Research/Science 9 months ago

Androgenic alopecia (AGA) might have evolved to reduce prostate cancer risk by increasing UV exposure to the scalp, but this theory is debated. Treatments like minoxidil and finasteride are used for AGA, though the exact causes and evolutionary reasons for hair loss are unclear.

community Is Adenosine + caffeine good combo or does caffeine cancels Adenosine affect?

2 upvotes 3 years ago

The conversation discusses using a liposomal gel with Adenosine and caffeine for hair loss, questioning if caffeine's role as an adenosine receptor antagonist might counteract the benefits of Adenosine or worsen hair loss.

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