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research The Enigma of the Stigma of Hair Loss: Why is Cancer-Treatment Related Alopecia so Traumatic for Women?

20 citations , November 2013 in “The Open Cancer Journal”

This observational study provides cause-specific mortality estimates to help patients and physicians better understand long-term outcomes for localized prostate cancer based on initial treatment choices.

Oncological Therapies and Hair Disorders: A Narrative Approach on Permanent Chemotherapy-Induced Alopecia. A Literature Review of Cancer-Related Therapies and Their Associated Hair and Scalp Disorders

research BI39 Oncological therapies and hair disorders: a narrative approach on permanent chemotherapy-induced alopecia. A literature review of cancer-related therapies and their associated hair and scalp disorders

June 2024 in “British Journal of Dermatology”

This narrative focuses on the experiences of two women with permanent chemotherapy-induced alopecia, highlighting the severe psychological and social impact along with dissatisfaction over pre-treatment information about hair loss, which they initially believed to be temporary.

research Hair loss in the elderly

November 2011

This review discusses types of hair loss in elderly women, highlighting diagnostic challenges and treatment limitations, but does not present new research findings.

research Oxidative stress management in the hair follicle: Could targeting NRF2 counter age‐related hair disorders and beyond?

30 citations , July 2017 in “BioEssays”

This review discusses the potential benefits of activating NRF2 for treating hair follicle disorders linked to oxidative stress and reports no new clinical results.

research Exploring Challenges Related to Breast Cancer Chemotherapy Among Females in Pakistan: A Qualitative Study

November 2025 in “Cancer Reports”

In this study, women who underwent chemotherapy for breast cancer in Islamabad, Pakistan, reported significant physical and psychological challenges, as well as economic strain; the authors concluded that government support and improved pre-treatment counseling could help mitigate these issues.

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community Surprise Hair Loss Breakthrough: A Sugar Gel Triggers Robust Regrowth

445 upvotes 1 year ago

A sugar gel was claimed to trigger hair regrowth, but users reported no results and potential cancer risks. The discussion included comparisons to minoxidil and skepticism about the effectiveness of the sugar treatment.

community Amplifica Sees Positive Results for Hair Loss Treatment - Results Show 15% increase in 60 days!

103 upvotes 1 year ago

Amplifica's new injectable treatment for androgenetic alopecia shows a 15% increase in hair thickness and coarseness in 60 days. The treatment is in early human trials and offers a promising alternative to hormone-related hair loss treatments.

community Will dht levels increased by creatine cancel out with finasteride

8 upvotes 1 year ago

Creatine may increase DHT levels, but its impact on hair loss is unclear and not well-studied. Many users report no significant hair loss while using creatine alongside finasteride, though some experience increased shedding.

community Federal Grant Cuts have impacted PP405 related research

459 upvotes 1 year ago

Federal funding cuts have delayed PP405 research, affecting hair loss treatment progress, though clinical trials will continue. The discussion highlights PP405's potential compared to minoxidil and finasteride and stresses the importance of government-funded research.

community Evolution theory: AGA is your body trying to reduce the risk of prostate cancer by exposing your scalp to more UV

in Research/Science 9 months ago

Androgenic alopecia (AGA) might have evolved to reduce prostate cancer risk by increasing UV exposure to the scalp, but this theory is debated. Treatments like minoxidil and finasteride are used for AGA, though the exact causes and evolutionary reasons for hair loss are unclear.

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Learn

7 / 10 results

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Overview

learn Bicalutamide

a nonsteroidal anti-androgen, most commonly used orally for women

learn Cyproterone

a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

learn Thymosin Beta 4

learn Tofacitinib

What are the key limitations and considerations surrounding tofacitinib in hair loss products and therapies? Reported hair regrowth with tofacitinib comes from alopecia areata, an autoimmune condition — mostly from small, non-randomized studies, with relapse common after stopping. There is no good evidence it helps pattern hair loss, and it is not approved for hair loss anywhere.
What types of hair loss conditions are most commonly associated with tofacitinib use in clinical settings? Published studies link tofacitinib mainly to alopecia areata and its severe variants — as an off-label drug being studied for them, not as a cause of hair loss. The evidence is mostly small, open-label or retrospective, and relapse after stopping is commonly reported.

learn TDM-105795

What types of alopecia or hair loss conditions might TDM-105795 be designed to target based on current research? TDM-105795 may target non-scarring alopecia, particularly androgenetic alopecia.

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