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research Assessment of Serum Level of Brain-Derived Neurotrophic Factor (BDNF) In Pediatric Alopecia Areata: A Case - Control Study

September 2025

This study found that pediatric alopecia areata patients had significantly lower serum BDNF levels compared to healthy controls, which were associated with greater alopecia severity, higher depressive symptoms, and poorer quality of life.

research Correlation between serum brain-derived neurotrophic factor level and depression severity in alopecia areata patients

1 citations , June 2022 in “International Journal of Health Sciences”

This study found that lower serum BDNF levels were associated with higher depression severity and more severe alopecia areata in patients.

research Association of iron levels in hair with brain structures and functions in young adults

8 citations , November 2019 in “Journal of Trace Elements in Medicine and Biology”

Higher hair iron levels are linked to changes in brain structure and function.

research Androgens and the Female Brain: The Relationship between Testosterone Levels, Depression, Anxiety, Cognitive Function, and Emotion Processing in Females with Polycystic Ovarian Syndrome

1 citations , January 2019

In this study, females with PCOS experienced greater depressive symptoms and cognitive impairment linked to high testosterone levels, but anti-androgen treatment significantly improved mood and cognitive function.

research Association between Serum Brain-derived Neurotrophic Factor and 25-OH Vitamin D Levels with Vitamin D Receptors Gene Polymorphism (rs2228570) in Patients with Autoimmune Thyroiditis and Hypothyroidism

7 citations , August 2021 in “Open Access Macedonian Journal of Medical Sciences”

In this case–control study, the researchers in Ukraine found no significant link between VDR rs2228570 polymorphism and decreased serum BDNF levels, though they observed a moderate correlation between serum BDNF and 25-OH Vitamin D levels in patients with thyroid disorders.

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community How finasteride lowers brain's happiness steroid allopregnanolone and causes depression: systemic dihydroprogesterone crosses blood brain barrier, you don't even need finasteride and brain 5ar for that

288 upvotes 1 year ago

Finasteride may lower allopregnanolone levels, potentially affecting mood, but many users report improved mental health due to reduced hair loss. Experiences with finasteride and dutasteride vary, with some experiencing side effects and others finding them beneficial for hair retention and overall happiness.

community Anyone experience lower energy levels while taking fin?

6 upvotes 10 years ago

Taking finasteride can lead to lower energy levels and "brain fog." Users report decreased mental cognition and libido.

community My thoughts on the FUD surrounding Finasteride

in Finasteride/Dutasteride 4 upvotes 5 years ago

Finasteride can increase testosterone levels and improve mood, with temporary side effects like brain fog that usually subside. The user reports positive results with finasteride, experiencing no hair loss and maintaining mental clarity after six months.

community How come dutasteride doesn't lower allopregnanolone, but finasteride does?

12 upvotes 1 year ago

Finasteride significantly lowers allopregnanolone levels, while dutasteride's effect is less clear and may vary. Some users speculate that dutasteride might be healthier for the brain due to its different inhibition pathways.

community Dutasteride experience and blood work results 1 1/2 years later

in Finasteride/Dutasteride 1 upvotes 1 year ago

The user shared their experience with dutasteride for hair loss prevention, noting side effects like muscle weakness and brain fog, and observed increased testosterone levels. They recommend starting with a low dose and adjusting based on individual needs and blood work results.

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Learn

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learn Valproic acid

an anticonvulsant repurposed for hair loss via histone inhibition

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Rice Bran

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Experts

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Alison Brain
United Kingdom

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Alison Brain