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GlossaryFree Testosterone (Unbound Testosterone)

unbound testosterone available for immediate use by tissues

Free Testosterone refers to the fraction of testosterone in the bloodstream that is not bound to proteins like sex hormone-binding globulin (SHBG) or albumin. This unbound testosterone is biologically active and readily available for tissues to use, playing a crucial role in various bodily functions such as muscle growth, mood regulation, and sexual health.

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research Plasma C19 Steroid Sulfate Levels and Indices of Androgen Bioavailability in Female Pattern Androgenic Alopecia

32 citations , January 1990 in “Clinical Endocrinology”

Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.

research Androgens

29 citations , November 1975 in “Clinics in endocrinology and metabolism”

Testosterone is made by Leydig cells, is active when not bound to proteins, and works by binding to receptors in muscles and other tissues.

research Sex Hormone Levels and Body Hair Growth in !Kung San and Kavango Men from Namibia

25 citations , October 1993 in “American Journal of Physical Anthropology”

Lower DHT levels lead to more body hair growth.

research Serum Testosterone and Sex Hormone Binding Globulin Levels in Women with Androgenetic Alopecia

November 1986 in “PubMed”

Women with androgenetic alopecia have lower SHBG levels.

research Advances in Male Hormone Substitution Therapy

23 citations , August 2005 in “Expert opinion on pharmacotherapy”

New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.

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community I've been afflicted by post finasteride syndrome, what now?

in Finasteride 38 upvotes 7 years ago

A user experienced severe side effects from finasteride, including mental health issues and physical symptoms, and sought advice on managing post-finasteride syndrome. Suggestions included checking vitamin levels, considering dopamine agonists, and avoiding further psychiatric medications.

community Just got my bloodwork done, should I worry?

in Finasteride/Dutasteride 9 upvotes 4 years ago

The conversation discusses concerns about potential side effects, specifically gynecomastia, from taking 1mg of finasteride every other day for hair loss. Bloodwork results were shared, but more information was requested to provide advice.

community Testosterone and Estradiol levels on 1 mg/day dutasteride

in Finasteride/Dutasteride 43 upvotes 5 months ago

A 30-year-old man experienced significant hair regrowth and improved libido after using finasteride and dutasteride for androgenetic alopecia, with no adverse effects. He plans to reduce dutasteride dosage when trying to conceive and has been using topical minoxidil since 2015.

community Is this real chat? Finasteride -> fountain of youth and longevity drug?

in Finasteride/Dutasteride 558 upvotes 6 months ago

Finasteride is discussed as a hair loss treatment with benefits like reduced prostate enlargement and skin aging, but it is not seen as a "fountain of youth." Users report mixed experiences, including side effects like decreased libido and dry eyes.

community "Creatine causes hair loss" myth debunked once and for all

in Research/Science 20 upvotes 3 years ago

Creatine does not directly cause hair loss but may increase DHT levels, potentially worsening hair loss in those predisposed to male pattern baldness. Users have mixed experiences, with some reporting increased shedding and others seeing no effect.

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